We're moving to rndsystems.com. Come with us!

After August 17, 2026, Novus Biologicals products and services will no longer be available on this website; you will access all products and services on rndsystems.com. Create your R&D Systems online account today.

BMP-2/BMP-4 Products

Antibodies
BMP-2/BMP-4 Antibody (100230) ...
BMP-2/BMP-4 Antibody (100230) [Unc...
MAB3552
355-BM) induces alkaline phosphatase production in the the ATDC5 mouse chondrogenic cell line in a dose-dependent manner (orange line). Alkaline Phosphatase Production elicited by Recombinant Human BMP-2 (1 µg/mL) is neutralized (green line) by increasing concentrations of Mouse Anti-Human BMP-2/BMP-4 Monoclonal Antibody (Catalog # MAB3552). The ND50 is typically 5-15 µg/mL in the presence of heparin (2 µg/mL)." class="big_lightbox" target="_blank"> Neutralization BMP-2/BMP-4 Antibody (100230) [Unconjugated]
Species: Hu
Applications: WB, B/N
Host: Mouse Monoclonal
BMP-2/BMP-4 Antibody [Unconju ...
BMP-2/BMP-4 Antibody [Unconjugated]
AF355
VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to the cytoplasm. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents." class="big_lightbox" target="_blank"> Immunohistochemistry BMP-2/BMP-4 Antibody [Unconjugated]
Species: Hu
Applications: WB, IHC
Host: Goat Polyclonal

Description

BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. BMP2 and 4 are members of the TGF-beta family, consisting of disulfide-linked homodimers. Both interact with GREM2 and SOSTDC1 and induce bone and cartilage formation. BMP4 also acts in mesoderm induction, tooth development, limb formation and fracture repair.

Bioinformatics

Product By Gene ID 650
Alternate Names
  • BDA2
  • BMP-2
  • BMP2A
  • BMP-2A
  • BMP2ABone morphogenetic protein 2A
  • bone morphogenetic protein 2

Research Areas for BMP-2/BMP-4

Find related products by research area and learn more about each of the different research areas below.

Cytokine Research
Embryonic Stem Cell Markers
Immunology
Neuronal Cell Markers
Neuronal Stem Cell Markers
Stem Cell Markers
Stem Cell Signaling Pathway