BMP-2/BMP-4 Antibody (100230) [Allophycocyanin] Summary
                         
                                
                                
                                
            | Immunogen | 
            Chinese hamster ovary cell line CHO-derived recombinant human BMP-2 Gln283-Arg396 Accession # P12643  | 
        
            | Specificity | 
            Detects human BMP-2 and human BMP-4 in direct ELISAs and Western blots. In direct ELISAs, 100% cross-reactivity with recombinant zebra fish (rzf) BMP-2 and rhBMP-4, 20%-40% cross-reactivity with rhBMP-3, -3b, -6, and no cross-reactivity with rhBMP-5, -7, -10, or -15 is observed.
   | 
        
            | Isotype | 
            IgG1  | 
        
            | Clonality | 
            Monoclonal  | 
        
            | Host | 
            Mouse  | 
        
            | Gene | 
            BMP2  | 
        
            | Purity | 
            Protein A or G purified from hybridoma culture supernatant  | 
        
            | Innovator's Reward | 
            Test in a species/application not listed above to receive a full credit towards a future purchase.  | 
        
                                
                          Applications/Dilutions
                                
                                    
                                    
                                        
                              
                                  | Dilutions | 
                                  
                                      - Neutralization 
 - Western Blot 
 
                                       
                                   | 
                              
            | Application Notes | 
            Optimal dilution of this antibody should be experimentally determined.  | 
        
                                    
                                  Packaging, Storage & Formulations
            | Storage | 
            Store at 4C in the dark.  | 
        
            | Buffer | 
            PBS  | 
        
            | Preservative | 
            0.05% Sodium Azide  | 
        
            | Purity | 
            Protein A or G purified from hybridoma culture supernatant  | 
        
Alternate Names for BMP-2/BMP-4 Antibody (100230) [Allophycocyanin]
                     Background
 
                    
                    BMPs (bone morphogenetic proteins) belong to the TGF beta superfamily of structurally related signaling proteins. Members of this superfamily are widely represented throughout the animal kingdom and have been implicated in a variety of developmental processes. BMP2 and 4 are members of the TGF-beta family, consisting of disulfide-linked homodimers. Both interact with GREM2 and SOSTDC1 and induce bone and cartilage formation. BMP4 also acts in mesoderm induction, tooth development, limb formation and fracture repair.
                      Limitations
 
                    
                    This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are 
guaranteed for 1 year from date of receipt.
 
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Applications: ELISA, ICC/IF, WB
                                     
                                 
                              
                            
                                  
                                       
                                                
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                                                Species: Hu
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                Secondary Antibodies
                    
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                Isotype Controls
                    
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