Rat BDNF ELISA Kit (Colorimetric)

Product Discontinued

Rat BDNF ELISA Kit (Colorimetric) Summary

• Description: Bdnf (Rat) ELISA Kit is a sandwich enzyme immunoassay for the quantitative measurement of rat Bdnf.
• Specificity: brain derived neurotrophic factor
• Standard Curve Range: 31.2 to 2000 pg/mL
• Sensitivity: 2 pg/mL
• Assay Type: Sandwich ELISA
• Inter-Assay: CV% < 7.1%
• Intra-Assay: CV% < 3.8%
• Sample Volume: 100 uL
• Kit Type: ELISA Kit (Colorimetric)
• Gene: BDNF

Applications/Dilutions

• Dilutions:
  • ELISA
  • Quantification
• Application Notes: Useful for quantification.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for Rat BDNF ELISA Kit (Colorimetric)

• Abrineurin
• ANON2
• BDNF
• brain-derived neurotrophic factor
• BULN2
• MGC34632
• Neurotrophin

Background

FUNCTION: Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. The versatility of BDNF is emphasized by its contribution to a range of adaptive neuronal responses including long-term potentiation (LTP), long-term depression (LTD), certain forms of short-term synaptic plasticity, as well as homeostatic regulation of intrinsic neuronal excitability. SUBUNIT: Monomers and homodimers. Binds to NTRK2/TRKB. SUBCELLULAR LOCATION: Secreted protein. POst translation modification: Converted into mature BDNF by plasmin (PLG). SIMILARITY: Belongs to the NGF-beta family. BDNF belongs to the neurotrophin family and regulates the survival and differentiation of neurons during development. The alterations in BDNF expression induced by various kinds of brain insult including stress, ischemia, seizure activity and hypoglycemia, may contribute to some pathologies such as depression, epilepsy, Alzheimer's, and Parkinson's disease.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. ELISA Kits are guaranteed for 6 months from date of receipt.

Publications for BDNF ELISA Kit (KA0330)(16)

Publications using KA0330

• Wang ML, Yu XJ, Li XG et al. Blockade of TLR4 within the Paraventricular Nucleus Attenuates Blood Pressure by Regulating ROS and Inflammatory Cytokines in Prehypertensive Rats. Am J Hypertens 2018-05-15 [PMID: 29767672]
• Guerrero-Cignarella A, Luna Diaz LV, Balestrini K et al. Differences in vaping topography in relation to adherence to exclusive electronic cigarette use in veterans. PLoS One 2018-04-25 [PMID: 29694428]
• Chang H, Wang Y, Tung C et al. 7, 8-Dihydroxyflavone, a Tropomyosin-Kinase Related Receptor B Agonist, Produces Fast-Onset Antidepressant-Like Effects in Rats Exposed to Chronic Mild Stress. Psychiatry Investigation 2016-04-06 [PMID: 27757132]
• Stefanova NA, Muraleva NA, Maksimova KY et al. An antioxidant specifically targeting mitochondria delays progression of Alzheimer's disease-like pathology. Aging (Albany NY) 2016-10-06 [PMID: 27750209]
• Teske JA, Perez-Leighton CE, Noble EE et al. Effect of Housing Types on Growth, Feeding, Physical Activity, and Anxiety-Like Behavior in Male Sprague-Dawley Rats. Front Nutr 2016-02-04 [PMID: 26870735] (ELISA)
• Park WS, Sung SI, Ahn SY et al. Optimal Timing of Mesenchymal Stem Cell Therapy for Neonatal Intraventricular Hemorrhage. Cell Transplant 2015-10-05 [PMID: 26440762]
• Lee B, Sur B, Shim I et al. Angelica gigas ameliorate depression-like symptoms in rats following chronic corticosterone injection BMC Complement Altern Med 2015-07-03 [PMID: 26138544] (ELISA, Rat)
• Vazquez E, Barranco A, Ramirez M et al. Effects of a human milk oligosaccharide, 2-fucosyllactose, on hippocampal long-term potentiation and learning capabilities in rodents J Nutr Biochem. 2015-01-15 [PMID: 25662731]
• Rudnitskaya EA, Maksimova KY, Muraleva NA et al. Beneficial effects of melatonin in a rat model of sporadic Alzheimer's disease. Biogerontology. 2014-12-17 [PMID: 25515660]
• Altmann P, Mildner M, Haider T et al. Secretomes of apoptotic mononuclear cells ameliorate neurological damage in rats with focal ischemia. F1000Res. 2014-01-01 [PMID: 25383184] (ELISA, Rat)
• Kaiser A, Kale A, Novozhilova E et al. Brain stem slice conditioned medium contains endogenous BDNF and GDNF that affect neural crest boundary cap cells in co-culture. Brain Res. 2014-04-16 [PMID: 24746495]
• Baranowska-Bosiacka I, Struzynska L, Gutowska I et al. Perinatal exposure to lead induces morphological, ultrastructural and molecular alterations in the hippocampus. Toxicology. 2012-11-09 [PMID: 23146751]
• Huang KF, Hsu WC, Chiu WT, Wang JY. Functional improvement and neurogenesis after collagen-GAG matrix implantation into surgical brain trauma. Biomaterials. 2011-12-09 [PMID: 22169139]
• Kovalchuk Y, Hanse E, Kafitz KW et al. Postsynaptic Induction of BDNF-Mediated Long-Term Potentiation. Science 2002-03-01 [PMID: 11872844]
• Lyons WE, Mamounas LA, Ricaurte GA et al. Brain-derived neurotrophic factor-deficient mice develop aggressiveness and hyperphagia in conjunction with brain serotonergic abnormalities. Proc Natl Acad Sci U S A 1999-12-21 [PMID: 10611369]
• Jones KR, Reichardt LF. Molecular cloning of a human gene that is a member of the nerve growth factor family. Proc Natl Acad Sci U S A. 1990-10-01 [PMID: 2236018]

FAQs for BDNF ELISA Kit (KA0330). (Showing 1 - 1 of 1 FAQs).

1. wondering what the difference is between your quantikine and duo set elisas?
   • Usually the duosets do not have the entire kit such as plates and buffers, whereas the other kits are complete.

Bioinformatics

• Gene Symbol: BDNF