BCR Antibody (1E11G12) - BSA Free

Images

 
Western Blot: BCR Antibody (1E11G12) [NBP2-61707] - Analysis using BCR mAb against HEK293 (1) and BCR (AA: 139-280)-hIgGFc transfected HEK293 (2) cell lysate.
Flow Cytometry: BCR Antibody (1E11G12) [NBP2-61707] - Analysis of K562 cells using BCR mouse mAb (green) and negative control (red).
Western Blot: BCR Antibody (1E11G12) [NBP2-61707] - Analysis using BCR mAb against human BCR (AA: 139-280) recombinant protein. (Expected MW is 41.6 kDa)
Western Blot: BCR Antibody (1E11G12) [NBP2-61707] - Analysis using BCR mouse mAb against Jurkat (1), Hela (2), and Ramos (3) cell lysate.
ELISA: BCR Antibody (1E11G12) [NBP2-61707] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow
Clone
1E11G12
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

Order Details

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Catalog# & Formulation Size Price

BCR Antibody (1E11G12) - BSA Free Summary

Immunogen
Purified recombinant fragment of human BCR (AA: 139-280) expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
BCR
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • ELISA 1:10000
  • Flow Cytometry 1:200-1:400
  • Western Blot 1:500-1:2000
Theoretical MW
142.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Concentration
1 mg/ml
Purity
Protein G purified

Alternate Names for BCR Antibody (1E11G12) - BSA Free

  • ALL
  • ALLD22S11
  • BCR
  • BCR1
  • breakpoint cluster region protein
  • breakpoint cluster region
  • CMLEC 2.7.11.1
  • D22S662
  • PHL
  • PHLFLJ16453
  • Renal carcinoma antigen NY-REN-26

Background

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol BCR