BCR Products

Antibodies
BCR Antibody
BCR Antibody
NBP1-19097
Species: Hu, Primate
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, PLA
Host: Rabbit Polyclonal
BCR Antibody
BCR Antibody
NBP1-19098
Species: Hu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP, PLA
Host: Rabbit Polyclonal
BCR Antibody
BCR Antibody
AF5129
Species: Hu
Applications: WB
Host: Sheep Polyclonal
Lysates
BCR Overexpression Lysate (De ...
BCR Overexpression Lysate (Denatured)
H00000613-T01
Species: Hu
Applications: WB
BCR Overexpression Lysate (Na ...
BCR Overexpression Lysate (Native)
NBP2-06527
Applications: WB
Proteins
BCR Partial Recombinant Prote ...
BCR Partial Recombinant Protein
H00000613-Q01
Species: Hu
Applications: WB, ELISA, PA
BCR Recombinant Protein Antig ...
BCR Recombinant Protein Antigen
NBP1-89137PEP
Species: Hu
Applications: AC
RNAi
BCR RNAi
BCR RNAi
H00000613-R03
Species: Hu
BCR RNAi
BCR RNAi
H00000613-R04
Species: Hu

Description

The breakpoint cluster region protein (Bcr) is best know to be involved in genomic translocation with fusion partner Abl (Cbr-Abl) causing chronic myelogenous leukemia (CML) (1-2). This 160 kDa protein contains a serine/threonine kinase domain, an SH2 binding domain, a GTP/GDP exchange domain and a C-term domain which functions as a GTPase activating protein for p21rac and CDC42 (3). Additionally, Bcr is involved in signal transduction and can down regulate Ras mediated cell signaling (4).

Bioinformatics

Entrez Human
Rat
Uniprot Human
Human
Human
Human
Product By Gene ID 613
Alternate Names
  • Renal carcinoma antigen NY-REN-26
  • breakpoint cluster region protein
  • D22S662
  • PHLFLJ16453
  • CMLEC 2.7.11.1
  • ALLD22S11
  • BCR1
  • breakpoint cluster region

Research Areas for BCR

Find related products by research area and learn more about each of the different research areas below.

Phospho-Specific
Protein Kinase
Signal Transduction

Bioinformatics Tool for BCR

Discover related pathways, diseases and genes to BCR. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
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