Angiopoietin-2 Antibody (5A9) - BSA Free

ELISA: Angiopoietin-2 Antibody (5A9) [NBP3-26508] - The Binding Activity of Angiopoietin-2 with Angiopoietin-2 Antibody. Activity: Measured by its binding ability in a functional ELISA. Immobilized Human Angiopoietin-2 at 2 ug/mL can bind Angiopoietin-2 Antibody, the EC50 is 0.6666-0.8876 ng/mL.

• Reactivity: Hu
• Applications: ELISA
• Clone: 5A9
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: BSA Free

Angiopoietin-2 Antibody (5A9) - BSA Free Summary

• Description: Novus Biologicals Human Angiopoietin-2 Antibody (5A9) - BSA Free (NBP3-26508) is a recombinant monoclonal antibody validated for use in ELISA. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Additional Information: Recombinant monoclonal antibody expressed in HEK293F cells
• Immunogen: Recombinant Human Angiopoietin-2 protein [UniProt O15123]
• Source: HEK293
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: ANGPT2
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA

Packaging, Storage & Formulations

• Storage: Store at -20 to -70C. Avoid freeze-thaw cycles.
• Buffer: 50% Glycerol, 0.01M PBS, PH 7.4
• Preservative: 0.03% Proclin 300
• Purity: Affinity purified

Alternate Names for Angiopoietin-2 Antibody (5A9) - BSA Free

• AGPT2
• ANG2
• ANG-2
• angiopoietin 2
• Angiopoietin-2
• angiopoietin-2a
• angiopoietin-2B
• angiopoitin 2
• ANGPT2
• Tie2-ligand

Background

Angiopoietin 1 and Angiopoietin 2 are important for development of the endothelium, by regulating tyrosine phosphorylation of the membrane receptor Tie 2/Tek. Angiopoietin 2 is only 60% homologous with Angiopoietin 1. Angiopoietin 1 binding to Tie 2/Tek causes phosphorylation of the receptor. Angiopoietin 2 competes for this binding, and thus blocks receptor phosphorylation. Angiopoietin 2 expression occurs at sites of vascular remodeling: dorsal aorta and major aortic branches, ovary, placenta and uterus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: ANGPT2