Human VEGF-C Quantikine ELISA Kit

Product Details

Reactivity HuSpecies Glossary
Applications ELISA

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Human VEGF-C Quantikine ELISA Kit Summary

The Quantikine Human VEGF-C Immunoassay is a 4.5 hour solid-phase ELISA designed to measure human VEGF-C in cell culture supernates, serum, plasma, and saliva. It contains NS0-expressed recombinant human VEGF-C (Cys156Ser substituted) and has been shown to accurately quantitate the recombinant factor. Results obtained using recombinant human VEGF-C (wild type) and natural human VEGF-C showed... linear curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for naturally occurring human VEGF-C.
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Natural human VEGF-C, recombinant human VEGF-C (wild type), and recombinant human VEGF-C (Cys156Ser substituted)
Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using DVEC00.

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human VEGF-C Quantikine ELISA Kit

  • Flt4 ligand
  • Flt4-L
  • vascular endothelial growth factor C
  • Vascular endothelial growth factor-related protein
  • VEGF-C
  • VRPFLT4 ligand DHM


Vascular endothelial growth factor C (VEGF-C) is a homodimeric ligand of VEGF R3/Flt-4 and is synthesized with N- and C-terminal propeptides. Fully processed VEGF-C containing only the VEGF homology domain can additionally bind and activate VEGF R2/KDR/Flk-1. VEGF-C interactions with VEGF R3 are critical for lymphangiogenesis. Both the ligand and receptor are usually co-expressed at sites of lymphatic vessel sprouting, in the embryo, and in various pathological conditions. Over-expression of VEGF-C in tumor cells induces tumoral lymphatic hyperplasia, neoangiogenesis, and vessel sprouting, resulting in enhanced lymph flow and metastasis to regional lymph nodes.

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⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to

Publications for VEGF-C (DVEC00)(51)

We have publications tested in 2 confirmed species: Human, Mouse.

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Showing Publications 1 - 10 of 51. Show All 51 Publications.
Publications using DVEC00 Applications Species
Szymczak, A;Kusztal, M;Go??biowski, T;Letachowicz, K;Go?dzik, A;Ko?cielska-Kasprzak, K;Tukiendorf, A;Krajewska, M; High Plasma Angiopoietin-2 Levels Predict the Need to Initiate Dialysis within Two Years in Patients with Chronic Kidney Disease International journal of molecular sciences 2023-06-12 [PMID: 37373181] (Human) Human
G Iwanek, B Ponikowska, A Zdanowicz, M Fudim, M Hurkacz, R Zymli?ski, P Ponikowski, J Biegus Relationship of Vascular Endothelial Growth Factor C, a Lymphangiogenesis Modulator, with Edema Formation, Congestion and Outcomes in Acute Heart Failure Journal of cardiac failure, 2023-04-29;0(0):. 2023-04-29 [PMID: 37121266] (Human) Human
J Suzuki, Y Shimizu, T Hayashi, Y Che, Z Pu, K Tsuzuki, S Narita, R Shibata, I Ishii, JW Calvert, T Murohara Hydrogen Sulfide Attenuates Lymphedema Via the Induction of Lymphangiogenesis Through a PI3K/Akt-Dependent Mechanism Journal of the American Heart Association, 2022-10-26;11(21):e026889. 2022-10-26 [PMID: 36285798] (Human) Human
J Zhong, HC Yang, EL Shelton, T Matsusaka, AJ Clark, V Yermalitsk, Z Mashhadi, LS May-Zhang, MF Linton, AB Fogo, A Kirabo, SS Davies, V Kon Dicarbonyl-modified lipoproteins contribute to proteinuric kidney injury JCI Insight, 2022-11-08;7(21):. 2022-11-08 [PMID: 36125905] (Human) Human
S Biswas Shi, Q Lu, D Sun, H Hou, JN Bulmer, BA Innes, DK Hapangama, GE Lash Platelet-derived growth factor BB is reduced in endometrial endothelial cells of women with abnormal uterine bleeding-endometrial disorder Oncogene, 2022-02-13;0(0):. 2022-02-13 [PMID: 35739007] (Human) Human
IS Miller, S Khan, LP Shiels, S Das, AC O' Farrell, K Connor, A Lafferty, B Moran, C Isella, P Loadman, E Conroy, S Cohrs, R Schibli, RS Kerbel, WM Gallagher, E Marangoni, K Bennett, DP O' Connor, RM Dwyer, AT Byrne Implementing subtype-specific pre-clinical models of breast cancer to study pre-treatment aspirin effects Cancer Medicine, 2022-04-17;0(0):. 2022-04-17 [PMID: 35434898] (Human) Human
Y Li, C Liu, X Zhang, X Huang, S Liang, F Xing, H Tian CCT5 induces epithelial-mesenchymal transition to promote gastric cancer lymph node metastasis by activating the Wnt/beta-catenin signalling pathway British Journal of Cancer, 2022-02-22;0(0):. 2022-02-22 [PMID: 35194191] (Human) Human
I Wada, S Nakao, M Yamaguchi, Y Kaizu, M Arima, S Sawa, KH Sonoda Retinal VEGF-A Overexpression Is Not Sufficient to Induce Lymphangiogenesis Regardless of VEGF-C Upregulation and Lyve1+ Macrophage Infiltration Investigative Ophthalmology & Visual Science, 2021-10-04;62(13):17. 2021-10-04 [PMID: 34673901] (Human) Human
T Mashima, T Wakatsuki, N Kawata, MK Jang, A Nagamori, H Yoshida, K Nakamura, T Migita, H Seimiya, K Yamaguchi Neutralization of the induced VEGF-A potentiates the therapeutic effect of an anti-VEGFR2 antibody on gastric cancer in vivo Scientific Reports, 2021-07-23;11(1):15125. 2021-07-23 [PMID: 34302038] (Mouse) Mouse
M Sevinc, NB Hasbal, T Basturk, PN Ozcafer, BB Kocas, K Kilickesme, A Ozel, T Sakaci, E Ahbap, A Unsal, Y Koc Comparison of lung ultrasound and other volumetric methods in peritoneal dialysis patients Medicine, 2021-01-22;100(3):e23856. 2021-01-22 [PMID: 33545952] (Human) Human
Show All 51 Publications.

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Product General Protocols

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FAQs for VEGF-C (DVEC00). (Showing 1 - 1 of 1 FAQs).

  1. I was wondering if you know of any blocking antibodies against IL-6 or VEGF-C that can be used in cell culture to quench these cytokines?
    • We have no antibodies that are currently known to show blocking antibodies to VEGF-C. Please see this link to our IL-6 antibodies with blocking/neutralizing activity can be found at this link.

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Gene Symbol VEGFC