AAAS Antibody

Western Blot: AAAS Antibody [NBP2-21596] - Sample (30 ug of whole cell lysate) A: 293T B: A431 7. 5% SDS PAGE gel, diluted at 1:1000.

Immunocytochemistry/Immunofluorescence: AAAS Antibody [NBP2-21596] - Immunofluorescence analysis of methanol-fixed HeLa, using antibody at 1:500 dilution.

Immunohistochemistry-Paraffin: AAAS Antibody [NBP2-21596] - Immunohistochemical analysis of paraffin-embedded Breast ca, using antibody at 1:500 dilution.

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

AAAS Antibody Summary

• Description: Novus Biologicals Rabbit AAAS Antibody (NBP2-21596) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. Anti-AAAS Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: Recombinant protein encompassing a sequence within the center region of human AAAS. The exact sequence is proprietary.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: AAAS
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Immunohistochemistry 10 - 1:500
  • Immunohistochemistry-Paraffin 1:100-1:1000
  • Western Blot 1:500-1:3000
• Theoretical MW: 60 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS, 1% BSA, 20% Glycerol
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for AAAS Antibody

• AAA
• AAASb
• achalasia, adrenocortical insufficiency, alacrimia (Allgrove, triple-A)
• achalasia, adrenocortical insufficiency, alacrimia
• ADRACALA
• Adracalin
• ALADIN
• Allgrove, triple-A
• DKFZp586G1624

Background

The protein encoded by this gene is a member of the WD-repeat family of regulatory proteins and may be involved in normal development of the peripheral and central nervous system. The encoded protein is part of the nuclear pore complex and is anchored there by NDC1. Defects in this gene are a cause of achalasia-addisonianism-alacrima syndrome (AAAS), also called triple-A syndrome or Allgrove syndrome. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Publications for AAAS Antibody (NBP2-21596)(1)

Publication using NBP2-21596

• Kane M, Rebensburg SV, Takata MA et al. Nuclear pore heterogeneity influences HIV-1 infection and the antiviral activity of MX2 Elife 2018-08-07 [PMID: 30084827] (WB, Human)

Bioinformatics

• Gene Symbol: AAAS
• Uniprot:
  • Q9NRG9(Human)