VPS4B Antibody - BSA Free

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263] - Staining of human endometrium shows moderate granular cytoplasmic positivity in in glandular cells.

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263] - Staining of human duodenum shows strong granular cytoplasmic positivity in glandular cells.

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263] - Staining of human urinary bladder shows moderate granular cytoplasmic positivity in in urothelial cells.

Immunohistochemistry-Paraffin: VPS4B Antibody [NBP2-49263] - Staining of human skeletal muscle shows no positivity in myocytes as expected.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

VPS4B Antibody - BSA Free Summary

• Immunogen: This antibody was developed against a recombinant protein corresponding to amino acids: AQKPVKEGQPSPADEKGNDSDGEGESDDPE
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: VPS4B
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:20 - 1:50
  • Immunohistochemistry-Paraffin 1:20 - 1:50
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended.
• Control Peptide:

  VPS4B Recombinant Protein Antigen (NBP2-49263PEP)

Reactivity Notes

Mouse (80%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for VPS4B Antibody - BSA Free

• Cell migration-inducing gene 1 protein
• Protein SKD1
• SKD1B
• SKD1cell migration-inducing 1
• Suppressor of K(+) transport growth defect 1
• suppressor of K+ transport defect 1
• vacuolar protein sorting 4 homolog B (S. cerevisiae)
• vacuolar protein sorting 4B (yeast)
• vacuolar protein sorting 4B
• vacuolar protein sorting-associated protein 4B
• VPS42
• VPS4-2

Background

VPS4B is encoded by this gene is a member of the AAA protein family (ATPases associated with diverse cellular activities), and is the homolog of the yeast Vps4 protein. In humans, two paralogs of the yeast protein have been identified. The former share a high degree of aa sequence similarity with each other, and also with yeast Vps4 and mouse Skd1 proteins. Mouse Skd1 (suppressor of K+ transport defect 1) has been shown to be a yeast Vps4 ortholog. Functional studies indicate that both human paralogs associate with the endosomal compartments, and are involved in intracellular protein trafficking, similar to Vps4 protein in yeast. The gene encoding this paralog has been mapped to chromosome 18; the gene for the other resides on chromosome 16. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VPS4B