A synthetic peptide from N-terminus of human VEGF protein.
Cytoplasmic, cell surface
This VEGF (vascular endothelial growth factor) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. This reacts with the 165, 189, and 121 amino acid splice variants of VEGF of human, and to a lesser extent, mouse and rat.
Protein A or G purified
Test in a species/application not listed above to receive a full credit towards a future purchase.
Intended Use: This product is intended for qualitative immunohistochemistry with normal and neoplastic formalin-fixed, paraffin-embedded tissue sections, to be viewed by light microscopy. Clinical interpretation of staining results should be accompanied by histological studies with proper controls. Patients? clinical histories and other relevant diagnostic tests should be utilized by a qualified person(s) when evaluating and interpreting results. Staining Protocol: We suggest an incubation period of 30 minutes at room temperature. Optimal incubation conditions should be determined by the user based upon the fixation conditions and staining system employed. No pretreatment is required for formalin fixed paraffin tissue sections. This product has a prediluted size available. If a 6mL or 7mL pre-diluted size is purchased this product can be used Neat (without further dilution). Use recommended dilution for the concentrated vials only.
Alternate Names for VEGF Antibody (SP28)
vascular endothelial growth factor A
Vascular permeability factor
VPFvascular endothelial growth factor
VEGF (Vascular Endothelial Growth Factor) is a homodimeric, disulfide-linked glycoprotein involved in angiogenesis which promotes tumor progression and metastasis. It exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium. Of the four isoforms of VEGF, the smaller two, VEGF 165 and VEGF 121, are secreted proteins and act as diffusible agents, whereas the larger two (VEGF 189 and VEGF 206) remain cell associated.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
FAQs for VEGF Antibody (NBP1-22844). (Showing 1 - 1 of 1 FAQ).
Why is the molecular weight of VEGF different from the similar antibody, for some companies the the molecular weight is 40KD)?
I can't comment on another company's antibody because I don't have any information about their products. I can tell you that VEGF is expressed in a variety of isoforms and is subject to various post-translational modifications that influence its apparent molecular weight in an SDS-PAGE gel compared to the theoretical molecular weight.
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