VEGF Products

Antibodies
VEGF Antibody [Unconjugated] ...
VEGF Antibody [Unconjugated] - 164
AF-493-NA
Species: Mu
Applications: WB, IHC, ELISA(Cap), Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
VEGF Antibody [Unconjugated] ...
VEGF Antibody [Unconjugated] - 164
AF-293-NA
Species: Hu
Applications: WB, ICC, Neut
Host: Goat Polyclonal
Conjugate Catalog # Availability Size Price
ELISA Kits
Rat VEGF ELISA Kit
Rat VEGF ELISA Kit
KA0430
Species: Rt
Human VEGF ELISA Kit
Human VEGF ELISA Kit
NBP1-91272
Species: Hu
Applications: ELISA
Mouse VEGF ELISA Kit
Mouse VEGF ELISA Kit
NBP1-92679
Species: Mu
Applications: ELISA
Lysates
VEGF Overexpression Lysate (D ...
VEGF Overexpression Lysate (Denatu...
H00007422-T01
Species: Hu
Applications: WB
VEGF Overexpression Lysate (N ...
VEGF Overexpression Lysate (Native)
NBL1-17712
Applications: WB
VEGF Overexpression Lysate (N ...
VEGF Overexpression Lysate (Native)
NBP2-09175
Applications: WB
Proteins
VEGF Blocking Peptide
VEGF Blocking Peptide
NB100-2381PEP
Species: Hu
Recombinant Human VEGF Protei ...
Recombinant Human VEGF Protein
NBC1-21277
Species: Hu
Applications: Func, PAGE
Recombinant Mouse VEGF Protei ...
Recombinant Mouse VEGF Protein
NBP1-30236
Species: Mu
Applications: Func, PAGE

Description

Vascular Endothelial Growth Factor (VEGF) is a homodimeric growth factor involved in both vasculogenesis and angiogenesis. These processes are required for proper blood supply during embryonic development, but they can also promote tumor progression and metastasis. VEGF exhibits potent mitogenic and permeability inducing properties specific for the vascular endothelium. Of the four isoforms of VEGF, the smaller two, VEGF 165 and VEGF 121, are secreted proteins and act as diffusible agents, whereas the larger two (VEGF 189 and VEGF 206) remain associated with the cell. VEGF antibodies are useful tools for embryonic development research and for use as tumor markers.

Bioinformatics

Entrez Human
Mouse
Rat
Uniprot Human
Human
Human
Mouse
Product By Gene ID 7422
Alternate Names
  • Vascular permeability factor
  • VEGF-A
  • VEGFMGC70609
  • VPFvascular endothelial growth factor
  • MVCD1
  • vascular endothelial growth factor A

Research Areas for VEGF

Find related products by research area and learn more about each of the different research areas below.

Angiogenesis
Cancer
Cell Biology
HIF Target Genes
Hypoxia

Bioinformatics Tool for VEGF

Discover related pathways, diseases and genes to VEGF. Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
 
Vizit™, under license from BioVista Inc.

Related VEGF Blog Posts

Check out the latest blog posts on VEGF.
The role of HIF-2 alpha in the progression and therapy of clear cell renal cell carcinoma
HIF-2 alpha, also known as hypoxia-inducible factor 2, endothelial PAS domain protein-1, and member of PAS superfamily 2 is part of the HIF family of proteins.  The HIF family is composed of HIF-1, HIF-2 and HIF-3, where HIF-2 is a dimeric protein...    Read more.
The application of CD31/Pecam-1 (MEC 7.46) in breast cancer research
CD31/PECAM-1, or platelet endothelial cell adhesion molecule 1, is a 130-kDa glycoprotein expressed on vascular and hematopoietic cells.  Depending on the cell type, CD31/PECAM-1 expression can be largely localized to cell junctions, playing a rol...    Read more.
The dynamic use of a PCNA antibody in fish, porcine and primate species
Proliferating cell nuclear antigen (PCNA) plays a crucial role in nucleic acid metabolism as it pertains to DNA replication and repair.  Most noted for its activation of subunits of DNA polymerase, it has also been found to interact with cell-cycl...    Read more.
The role of HIF-1 Alpha signaling in the retina under hypoxic conditions
Hypoxia inducible factor 1 (HIF-1) is a protein that plays an essential role in hypoxia, or low levels of cellular oxygen. HIF-1 is a heterodimeric protein that consists of a constitutively expressed beta subunit and oxygen related alpha subunit. ...    Read more.
Using SCP3/SYCP3 Antibodies as Meiosis Markers in Gametogenesis and DNA Repair Studies
The synaptonemal complex (SC) is a protein structure that forms during the synapsis of homologous chromosomes during meiosis. This structure is involved in the processes of chromosome synapsis, genetic recombination and subsequent chromosome segregati...    Read more.
Understanding the relationship between HIF-1 alpha, Hypoxia and Epithelial-Mesenchymal Transition
Epithelial-mesenchymal transition (EMT) is a natural process by which epithelial cells lose their polarity and intercellular adhesion, and gain the migratory invasive properties of mesenchymal stem cells that can differentiate into a variety of cel...    Read more.
Integrin alpha v beta 3 - a target for inhibiting tumor angiogenesis
Integrins are a family of transmembrane proteins involved in diverse processes including cell adhesion, signal transduction, cell migration, and differentiation. They exist as heterodimers consisting of noncovalently linked alpha and beta subunits....    Read more.
HIF-1 beta - activating gene transcription in response to hypoxia
Hypoxia-inducible factor 1 (HIF-1) is a heterodimeric transcription factor consisting of alpha and beta subunits. The levels of functional HIF-1 in the cell depends on the level of oxygen allowing cells to respond to hypoxic conditions. HIF-1a is a...    Read more.
HIF-1 alpha - sensing and responding to changing oxygen levels
Hypoxia-inducible factor 1 (HIF-1) allows cells to respond to changing levels of oxygen in the environment. HIF-1 is a heterodimeric transcription factor consisting of alpha and beta subunits. Under normal conditions HIF-1 alpha is continuously sy...    Read more.
VEGF: Vascular endothelial growth factor
VEGF is homodimeric, disulfide-linked glycoprotein cytokine that serves as the ligand for FLT1 (VEGFR-1 receptor) and FLK1 (VEGFR-2 receptor) tyrosine kinases. It is a key modulator of physiological angiogenesis, vasculogenesis, and endothelial cell g...    Read more.
LYVE1 - It's Alive! It's a LYVE
LYVE1 (lymphatic vessel endothelial hyaluronan receptor-1) is one of the most specific and widely used mammalian lymphatic endothelial markers.It is found in lymph nodes and at the luminal/abluminal surfaces of lymphatic vessels. It is a single-pass t...    Read more.
LOX: A prime enzyme
LOX is a copper-dependent amine oxidase enzyme that executes post-translational oxidative deamination on peptidyl lysine residues in precursors of fibrous collagen and elastin. LOX is secreted into the extracellular environment in an inactive form, wh...    Read more.
VEGF Receptors, Angiogenesis and Cancer
Vascular endothelial growth factor receptors 1 and 2 (VEGFR1 and VEGFR2) are related family members of the vascular endothelial growth factor (VEGF) family of membrane receptor tyrosine kinases. They are key regulators of physiological angiogenesis du...    Read more.
Controlling the HIF-1 Switch
Hypoxia-inducible factor-1 is a major transcription factor composed of two subunits: HIF-1alpha and HIF-1 beta. Under normoxic conditions, HIF-1 alpha is targeted to proteosomal degradation via ubiquitination. On the other hand during hypoxic conditio...    Read more.
The Role of the MMP2 Antibody in Colorectal Cancer Research
The enzymes of the Matrix Metalloproteinase (MMP) family assist in the degradation of the extracellular matrix, under both normal and pathological conditions. MMP antibodies have identified roles in a number of physiological processes, such as embryon...    Read more.
HIF-1 Beta Antibody Studies and Developments in Hypoxia Research
We at Novus Biologicals have a large HIF-1 (Hypoxia Inducible Factor-1) antibody catalog, with twenty HIF-1 beta antibody products specifically targeted to the beta subunit of HIF-1, a heterodimer which is known to contribute to many human diseases ar...    Read more.
Read more VEGF related blogs.