VEGF 165 Antibody (R012) - Azide and BSA Free

Neutralization: VEGF 165 Antibody (R012) [NBP2-89779] - Measured by its ability to neutralize VEGF165 induced proliferation of human umbilical vein endothelial cells (HUVEC). The Neutralization Titer (IC50) is typically 15-75ng/mL in the presence of 10 ng/mL Recombinant Human VEGF165.

• Reactivity: Hu, Pm-Cm
• Applications: B/N
• Clone: R012
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: Azide and BSA Free

VEGF 165 Antibody (R012) - Azide and BSA Free Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human/Cynomolgus VEGF 165 (Uniprot#: P15692-4; Met1-Arg191)
• Specificity: Has cross-reactivity in ELISA with:
  
  Mouse VEGF164
  Rat VEGF164
• Source: HEK293
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: VEGFA
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Neutralization

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for VEGF 165 Antibody (R012) - Azide and BSA Free

• MVCD1
• vascular endothelial growth factor A
• Vascular permeability factor
• VEGF-A
• VEGFMGC70609
• VPFvascular endothelial growth factor

Background

VEGF (Vascular endothelial growth factor) is the only growth factor that stimulates vascular permeability. It promotes endothelial proliferation and survival, angiogenesis, vasculognesis and inhibits apoptosis. VEGF mitogenic activity is specific for endothelial cell and that makes it distinct among other growth factors. VEGF is thought to be important in the pathophysiology of neuronal and other tumors, by functioning as a promter of angiogenesis for human gliomas. Human VEGF occurs in several molecular variants and the 165 form is the most common form in most tissues. Biological activities of VEGF are not species-specific and glycosylation is not required for biological activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: VEGFA