Flow Cytometry: VCAM-1/CD106 Antibody (MR106) [NBP1-43368] - Analysis using the Biotin conjugate of NBP1-43368. Staining of rat bone marrow cells with 0.125 ug of Mouse IgG1 kappa Isotype Control Biotin (left) or 0.125 ...read more
Flow Cytometry: VCAM-1/CD106 Antibody (MR106) [NBP1-43368] - Staining of rat bone marrow cells with 0.25 ug of Mouse IgG1 kappa Isotype Control Purified (open histogram) or 0.25 ug of Anti-Rat CD106 (VCAM-1) Purified ...read more
This MR106 antibody has been tested by flow cytometric analysis of rat bone marrow cells. This can be used at less than or equal to 0.5 ug per test. Cell number should be determined empirically but can range from 10^5to 10^8cells/test.
Read Publication using NBP1-43368 in the following applications:
The MR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin alpha4beta1 (VLA-4, CD49d/CD29) and Integrin alpha4beta7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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