WB, IP, AdBlk, ICCHost:
WB, Simple Western, ELISA, IHC, IHC-PHost:
WB, Simple Western, Flow, IHC, AdBlk, CyTOF-readyHost:
Applications: WB, IP
CD106 is a 110 kD glycosylphosphatidylinositol (GPI)-linked transmembrane protein, also known as VCAM-1 and INCAM-110. It is constitutively expressed on bone marrow stromal cells, myeloid progenitors, splenic dendritic cells, activated endothelial cells, as well as some lymphocytes. CD106 expression can be upregulated on endothelial cells by inflammatory cytokines. CD106 is involved in adhesion and acts as a counter-receptor for VLA-4 ( alpha4/ beta1 integrin) and LPAM-1 ( alpha4/ beta7 integrin). The 429 antibody has been reported to partially block VCAM-1-mediated binding.
Bioinformatics Tool for VCAM-1/CD106
Discover related pathways, diseases and genes to VCAM-1/CD106. Need help? Read the Bioinformatics Tool Guide
for instructions on using this tool.