Home » UCH-L1/PGP9.5 » UCH-L1/PGP9.5 Antibodies » UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680]

UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680]

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Product Discontinued
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    • Catalog Number
      NBP2-33130FR
    • Availability
      Product Discontinued

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UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680] Summary

Immunogen
Native UchL1 (PGP9.5) protein from brain was used as immunogen to generate the antibody (Day & Thompson, 1986).
Localization
Cytoplasmic, Endoplasmic Reticulum membrane
Marker
pan-Neuronal Marker
Specificity
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
UCHL1
Purity
Protein G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Theoretical MW
25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Zebrafish reactivity reported in scientific literature (PMID: 30377377).

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680]

  • EC 3.4.19.12
  • EC 6.-
  • Neuron cytoplasmic protein 9.5
  • PARK5
  • PGP 9.5
  • PGP9.5
  • PGP9.5Uch-L1
  • PGP95
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
  • ubiquitin carboxyl-terminal hydrolase isozyme L1
  • ubiquitin C-terminal hydrolase
  • Ubiquitin thioesterase L1
  • UCHL1
  • UCH-L1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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UCH-L1/PGP9.5
Antibody (31A3) [DyLi ...
NBP2-33130FR
UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680]
Species: Hu, Mu, Rt, Po, Bv, Ze
Applications: WB, ELISA

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Bioinformatics

Gene Symbol UCHL1
Entrez
Uniprot