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UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680]

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Product Details

Summary
Reactivity Hu, Mu, Rt, Po, BvSpecies Glossary
Applications WB, ELISA
Clone
31A3
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

View Available Conjugates
Catalog# & Conjugate Size Price
Alexa Fluor 405
NBP2-33130AF405
Alexa Fluor 488
NBP2-33130AF488
Alexa Fluor 647
NBP2-33130AF647
Alexa Fluor 700
NBP2-33130AF700
Biotin
NBP2-33130B
DyLight 350
NBP2-33130UV
DyLight 405
NBP2-33130V
DyLight 488
NBP2-33130G
DyLight 550
NBP2-33130R
DyLight 650
NBP2-33130C
DyLight 755
NBP2-33130IR
HRP
NBP2-33130H
Unconjugated
NB600-1160
View Available Formulations
Catalog# & Formulation Size Price
Standard Formulation
NB600-1160
Azide and BSA Free
NBP2-33130
IHC-Prediluted
NBP2-45339
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UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680] Summary

Immunogen
Native UchL1 (PGP9.5) protein from brain was used as immunogen to generate the antibody (Day & Thompson, 1986).
Localization
Cytoplasmic, Endoplasmic Reticulum membrane
Marker
pan-Neuronal Marker
Specificity
This MAb reacts with a protein of 20-30kDa, identified as PGP9.5, also known as ubiquitin carboxyl-terminal hydrolase-1 (UchL1). Initially, PGP9.5 expression in normal tissues was reported in neurons and neuroendocrine cells but later it was found in distal renal tubular epithelium, spermatogonia, Leydig cells, oocytes, melanocytes, prostatic secretory epithelium, ejaculatory duct cells, epididymis, mammary epithelial cells, Merkel cells, and dermal fibroblasts. Furthermore, immunostaining for PGP9.5 has been shown in a wide variety of mesenchymal neoplasms as well. A mutation in PGP9.5 gene is believed to cause a form of Parkinson's disease.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
UCHL1
Purity
Protein G purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
Theoretical MW
25 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680]

  • EC 3.4.19.12
  • EC 6.-
  • Neuron cytoplasmic protein 9.5
  • PARK5
  • PGP 9.5
  • PGP9.5
  • PGP9.5Uch-L1
  • PGP95
  • ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase)
  • ubiquitin carboxyl-terminal hydrolase isozyme L1
  • ubiquitin C-terminal hydrolase
  • Ubiquitin thioesterase L1
  • UCHL1
  • UCH-L1

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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UCH-L1/PGP9.5
Antibody (31A3) [DyLi ...
NBP2-33130FR
UCH-L1/PGP9.5 Antibody (31A3) [DyLight 680]
Species: Hu, Mu, Rt, Po, Bv
Applications: WB, ELISA

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Bioinformatics

Gene Symbol UCHL1
Entrez
Uniprot