Substance P Antibody (266815)

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Substance P was detected in immersion fixed paraffin-embedded sections of human spinal cord using 8 µg/mL Human/Mouse/Rat Substance P Monoclonal Antibody (Catalog # MAB4375) overnight at ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications IHC
Clone
266815
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

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Catalog# & Formulation Size Price

Substance P Antibody (266815) Summary

Immunogen
KLH-coupled mouse Substance P synthetic peptide
RPKPQQFFGLM
Specificity
Detects human, mouse, and rat Substance P.
Source
N/A
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TAC1
Purity
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry 8-25 ug/mL
Reviewed Applications
Read 1 Review rated 4
using
MAB4375 in the following application:

Publications
Read Publications using
MAB4375 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Protein A or G purified from hybridoma culture supernatant
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Substance P Antibody (266815)

  • neurokinin 1
  • neurokinin 2
  • neurokinin A
  • Neurokinin-1
  • neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
  • neuropeptide gamma
  • neuropeptide K
  • NK2
  • NKA
  • NKNAneurokinin alpha
  • NPK
  • PPT
  • protachykinin-1
  • substance K
  • Substance P
  • TAC1
  • TAC2neuromedin L
  • tachykinin 2
  • tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2
  • tachykinin, precursor 1

Background

Substance P (Neurokinin-1), is member of the tachykinin peptide family. Processing of preprotachykinin isoforms generates Substance P and other tachykinins. Active Substance P is an 11 amino acid peptide, RPKPQQFFGLM, that is identical across all mammalian species. Substance P is mainly secreted from C-type fibers of primary sensory afferent neurons after stimulation through protease-activated receptor 2 (PAR2). Substance P binds primarily to the neurokinin 1 receptor on neurons in the dorsal horn, transmitting pain signals through the central nervous system.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Substance P Antibody (MAB4375)(4)

Review for Substance P Antibody (MAB4375) (1) 41

Average Rating: 4
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using MAB4375:
Filter by Applications
IF
(1)
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Mouse
(1)
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Images Ratings Applications Species Date Details
 
reviewed by:
Anonymous
IF Mouse 02/20/2015
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Summary

ApplicationImmunofluorescence
Sample TestedSee PMID 23232501
SpeciesMouse

Blocking

Blocking DetailsSee PMID 23232501

Details

Detection NotesSee PMID 23232501

Comments

CommentsIndependent review from antibodyresource.com

FAQs for Substance P Antibody (MAB4375) (0)

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Secondary Antibodies

 

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Recent Reviews

4
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4
1
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2
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1
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Anonymous
02/20/2015
Application: IF
Species: Mouse

Bioinformatics

Gene Symbol TAC1
Entrez