TYRP1 Antibody (CL4923) - Azide and BSA Free

Staining of human tonsil shows no positivity in lymphoid cells as expected (negative control).

Staining of human skin shows strong cytoplasmic immunoreactivity in melanocytes.

Analysis in human cell line SK-MEL-30.

Staining of SK-MEL-30 cells using the Anti-TYRP1 monoclonal antibody) .

• Reactivity: Hu
• Applications: WB, ICC/IF, IHC
• Clone: CL4923
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free
• Concentration: LYOPH

TYRP1 Antibody (CL4923) - Azide and BSA Free Summary

• Immunogen: This antibody was generated using a recombinant protein sequence of P17643, with the exact immunogen sequence remaining proprietary.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TYRP1
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 2-10 ug/ml
  • Immunohistochemistry-Paraffin 1:1000 - 1:2500
  • Western Blot 1 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. For Immunocytochemistry/ Immunofluorescence/IF, PFA/Triton X-100 is recommended for fixation/permeabilization.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Lyophilized from a 0.2 um filtered solution in PBS with Trehalose
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Centrifuge the vial of lyophilized antibody at 12,000 x g for 20 seconds. Reconstitute by adding sterile, distilled water to achieve a final antibody concentration of 1mg/ml.

Alternate Names for TYRP1 Antibody (CL4923) - Azide and BSA Free

• b-PROTEIN
• CAS25,6-dihydroxyindole-2-carboxylic acid oxidase
• Catalase B
• CATB
• EC 1.14.18
• EC 1.14.18.-
• EC 1.14.18.1
• Glycoprotein 75
• GP75DHICA oxidase
• Melanoma antigen gp75
• TRP-1
• TRPTYRP
• tyrosinase-related protein 1TRP1
• TYRRP

Background

TYRP1 encodes a melanosomal enzyme that belongs to the tyrosinase family and plays an important role in the melanin biosynthetic pathway. Defects in this gene are the cause of rufous oculocutaneous albinism and oculocutaneous albinism type III. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TYRP1