TRPM2 Antibody

Images

 
Western Blot: TRPM2 Antibody [NBP1-33416] - HepG2 whole cell and membrane extracts (30 ug) were separated by 5% SDS-PAGE, and the membrane was blotted with TRPM2 antibody [N1N2-2], N-term diluted at 1:500. The ...read more
Immunohistochemistry-Paraffin: TRPM2 Antibody [NBP1-33416] - Paraffin-embedded rat liver. TRPM2 antibody [N1N2-2], N-term diluted at 1:500.
Immunohistochemistry-Paraffin: TRPM2 Antibody [NBP1-33416] - Paraffin-embedded MDAMB468 xenograft, using antibody at 1:100 dilution.

Product Details

Summary
Reactivity Hu, Rt, MuSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.17 mg/ml

Order Details

TRPM2 Antibody Summary

Immunogen
Recombinant protein encompassing a sequence within the N-terminus region of human TRPM2. The exact sequence is proprietary.
Localization
Membrane, Multi-pass membrane protein
Predicted Species
Mouse (90%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPM2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
  • Immunohistochemistry 1:100-1:1000
  • Immunohistochemistry-Paraffin 1:100-1:1000
Theoretical MW
171 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 20% Glycerol
Preservative
0.025% Proclin 300
Concentration
1.17 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TRPM2 Antibody

  • EC 3.6.1.13
  • EREG1MGC133383
  • Estrogen-responsive element-associated gene 1 protein
  • KNP3LTrpC-2
  • Long transient receptor potential channel 2
  • LTrpC2
  • LTRPC2TRPC7transient receptor potential cation channel subfamily M member 2
  • NUDT9H
  • NUDT9L1
  • transient receptor potential cation channel, subfamily M, member 2
  • Transient receptor potential channel 7
  • TrpC7

Background

TRPM2 belongs to the ion transport protein family. This family contains Sodium, Potassium, Calcium and ion channels. This family has 6 transmembrane helices in which the last two helices flank a loop which determines ion selectivity. TRPM2 is activated by oxidative stress and confers susceptibility to cell death.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for TRPM2 Antibody (NBP1-33416)

Discover related pathways, diseases and genes to TRPM2 Antibody (NBP1-33416). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on TRPM2.

Winter is coming, and TRPM8 welcomes the cold!
TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...  Read full blog post.

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Bioinformatics

Gene Symbol TRPM2