TRPM3 Antibody

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

TRPM3 Antibody Summary

Immunogen
A synthetic peptide from the 4th cytoplasmic loop of human TRPM3 conjugated to an immunogenic carrier protein was used as the immunogen. The antigen is homologous in rat, mouse, monkey and dog.
Specificity
Specific for TRPM3.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRPM3
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:300-1:2000
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:300-1:2000
Publications
Read Publication using NB100-98864.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
No Preservative
Concentration
LYOPH
Purity
Unpurified
Reconstitution Instructions
Reconstitute with 0.1 ml sterilized water to desired concentration.

Alternate Names for TRPM3 Antibody

  • EC 2.3.1.31
  • EC 5.99.1.3
  • Long transient receptor potential channel 3
  • LTrpC3
  • LTrpC-3
  • LTRPC3KIAA1616MLSN2GON-2
  • melastatin 2
  • melastatin-2
  • transient receptor potential cation channel subfamily M member 3
  • transient receptor potential cation channel, subfamily M, member 3

Background

The product of this gene belongs to the family of transient receptor potential (TRP) channels. TRP channels are cation-selective channels important for cellular calcium signaling and homeostasis. The protein encoded by this gene mediates calcium entry, and this entry is potentiated by calcium store depletion. Alternatively spliced transcript variants encoding different isoforms have been identified. FUNCTION: Calcium channel mediating constitutive calcium ion entry. Its activity is increased by reduction in extracellular osmolarity, by store depletion and muscarinic receptor activation. SUBCELLULAR LOCATION: Membrane; Multi-pass membrane protein. TISSUE SPECIFICITY: Expressed primarily in the kidney and, at lower levels, in brain, testis, ovary, pancreas and spinal cord. Expression in the brain and kidney was determined at protein level. In the kidney, expressed predominantly in the collecting tubular epithelium in the medulla, medullary rays, and periglomerular regions; in the brain, highest levels are found in the cerebellum, choroid plexus, the locus coeruleus, the posterior thalamus and the substantia nigra. Down-regulated in renal tumors compared to normal kidney.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRPM3 Antibody (NB100-98864)(1)


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Product General Protocols

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Video Protocols

WB Video Protocol

FAQs for TRPM3 Antibody (NB100-98864). (Showing 1 - 1 of 1 FAQ).

  1. We have been using your TRPM3 antibody (catalog number NB100-98864) for Immunohistochemistry and Immunocytochemistry for a few months now. There is one control that we need to follow up with and that is a pre-absorption control. Is it possible to purchase the immunogen from you?
    • The blocking peptide for this antibody can be ordered with the product number NB100-98864PEP.

Secondary Antibodies

 

Isotype Controls

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Blogs on TRPM3.

Winter is coming, and TRPM8 welcomes the cold!
TRPM8, or transient receptor potential melastatin 8, is a nonselective cation channel that is activated by cold environments and menthol-like cooling compounds.  While TRPM8 is best known for its location in peripheral nerve endings, it has functio...  Read full blog post.

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Bioinformatics

Gene Symbol TRPM3
Entrez
Uniprot