A synthetic peptide from the region around (and including) phospho Y816 site of rat TrkB (BDNF/NT-3 growth factors receptor, TrkB tyrosine kinase, Trk-B) conjugated to an immunogenic carrier protein was used as the immunogen.
subcellular location: membrane; single-pass type i membrane protein.
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Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Please note the larger size(s) come in lyophilized form and the sample size will be in liquid formate. Reconstitute with 0.5 ml sterilized water. Add glycerol (1:1) for additional stability.
Alternate Names for TrkB [p Tyr816] Antibody
BDNF/NT-3 growth factors receptor
Neurotrophic tyrosine kinase receptor type 2
neurotrophic tyrosine kinase, receptor, type 2
TrkB tyrosine kinase
TRKBBDNF-tropomyosine receptor kinase B
tyrosine kinase receptor B
Receptor for brain-derived neurotrophic factor (bdnf), neurotrophin-3 and neurotrophin-4/5 but not nerve growth factor (ngf). involved in the development and/or maintenance of the nervous system. this is a tyrosine-protein kinase receptor. known substrates for the trk receptors are shc1, pi-3 kinase, and plc-gamma-1.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
TrkB: Bridging Ontogenesis and Oncogenesis Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. Interaction of brain-derived neurotrophic factor (BDNF) with its... Read full blog post.
TrkB and Nervous System Function Neutrophins and their receptors play an important role in regulating the development of both the central and peripheral nervous systems. Neurotrophin ligand binding to each of their respective Trk cellular receptors is essential for the growth and sur... Read full blog post.
TrkB: Docking for Neurotrophins and Beyond. Tropomyosin receptor kinase B (TrkB) is a member of the Trk receptor tyrosine kinases family consisting of TrkA, TrkB and TrkC. The sequence of these family members is highly conserved. TrK's are activated by several neurotrophins, which are small pro... Read full blog post.
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