transgelin 2 Antibody - BSA Free

Immunocytochemistry/Immunofluorescence: transgelin 2 Antibody [NBP1-89722] - Staining of human cell line U-2 OS shows localization to cytosol & actin filaments. Antibody staining is shown in green.

Immunohistochemistry-Paraffin: transgelin 2 Antibody [NBP1-89722] - Staining of human tonsil shows moderate to strong positivity in germinal center cells.

Immunohistochemistry-Paraffin: transgelin 2 Antibody [NBP1-89722] - Staining of human placenta shows moderate to strong cytoplasmic positivity in trophoblastic cells.

Immunohistochemistry-Paraffin: transgelin 2 Antibody [NBP1-89722] - Staining of human lung shows moderate cytoplasmic positivity in macrophages.

Analysis in human cell line A-431.

Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ICC/IF, IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

transgelin 2 Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit transgelin 2 Antibody - BSA Free (NBP1-89722) is a polyclonal antibody validated for use in IHC, WB and ICC/IF. Anti-transgelin 2 Antibody: Cited in 5 publications. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: RGPAYGLSREVQQKIEKQYDADLEQILIQWITTQCRKDVGRPQPGRENFQNWLKDGTVLCELINALYPEGQAPVKKIQASTMAFKQMEQISQFLQAAERYGINTTDIFQTVDLWEGKNMACVQRTLMNLGGLA
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TAGLN2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 0.25-2 ug/ml
  • Immunohistochemistry 1:200 - 1:500
  • Immunohistochemistry-Paraffin 1:200 - 1:500
  • Western Blot 0.04-0.4 ug/ml
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval is recommended. ICC/IF Fixation Permeabilization: Use PFA/Triton X-100.
• Control Peptide:

  transgelin 2 Protein (NBP1-89722PEP)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Immunogen affinity purified

Alternate Names for transgelin 2 Antibody - BSA Free

• KIAA0120HA1756
• SM22-alpha homolog
• transgelin 2
• transgelin-2

Background

transgelin 2 is encoded by this gene is a homolog of the protein transgelin, which is one of the earliest markers of differentiated smooth muscle. The function of this protein has not yet been determined. [provided by RefSeq].

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for transgelin 2 Antibody (NBP1-89722)(6)

Publications using NBP1-89722

• Qiu X, Jiang M, Qu H et al. TAGLN2-mediated Actin Cytoskeleton Stabilization Promotes Proliferation and Metastasis of Ovarian Carcinoma Applied Immunohistochemistry & Molecular Morphology 2025-07-01 [PMID: 40247723]
• Wang H, Zhang X, Liu C et al. TAGLN2-Regulated Trophoblast Migration, Invasion and Fusion are Impaired in Preeclampsia Frontiers in Cell and Developmental Biology 2022-02-23 [PMID: 35281112]
• Liang X, Jin Y, Wang H et al. Transgelin 2 is required for embryo implantation by promoting actin polymerization FASEB J. 2019-01-31 [PMID: 30702937] (WB, Mouse)
• Stadler C, Hjelmare M, Neumann B et al. Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy. J Proteomics 2012-04-03 [PMID: 22361696]
• Nohata N, Sone Y, Hanazawa T et al. miR-1 as a tumor suppressive microRNA targeting TAGLN2 in head and neck squamous cell carcinoma. Oncotarget 2011-01-01 [PMID: 21378409]
• Yoshino H, Chiyomaru T, Enokida H et al. The tumour-suppressive function of miR-1 and miR-133a targeting TAGLN2 in bladder cancer. Br J Cancer 2011-03-01 [PMID: 21304530]

Bioinformatics

• Gene Symbol: TAGLN2