TRAF-2 Antibody (5C2C3)

Images

 
Western Blot: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis using TRAF2 mAb against human TRAF2 (AA: 39-188) recombinant protein. (Expected MW is 42.5 kDa)
Immunocytochemistry/ Immunofluorescence: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis of MCF-7 cells using TRAF2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa ...read more
Immunohistochemistry: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis of paraffin-embedded cervical cancer tissues using TRAF2 mouse mAb with DAB staining.
Flow Cytometry: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis of HepG2 cells using TRAF-2 mouse mAb (green) and negative control (red).
Western Blot: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis using TRAF2 mAb against HEK293 (1) and TRAF2 (AA: 39-188)-hIgGFc transfected HEK293 (2) cell lysate.
Immunocytochemistry/ Immunofluorescence: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis of HL-7702 cells using TRAF2 mouse mAb (green). Blue: DRAQ5 fluorescent DNA dye. Red: Actin filaments have been labeled with Alexa ...read more
Flow Cytometry: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Analysis of Hela cells using TRAF2 mouse mAb (green) and negative control (red).
ELISA: TRAF-2 Antibody (5C2C3) [NBP2-61661] - Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng)

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Clone
5C2C3
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

TRAF-2 Antibody (5C2C3) Summary

Immunogen
Purified recombinant fragment of human TRAF2 (AA: 39-188) expressed in E. Coli.
Isotype
IgG1
Clonality
Monoclonal
Host
Mouse
Gene
TRAF2
Purity
Protein G purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:2000
  • ELISA 1:10000
  • Flow Cytometry 1:200-1:400
  • Immunocytochemistry/Immunofluorescence 1:200-1:1000
  • Immunohistochemistry 1:200-1:1000
  • Immunohistochemistry-Paraffin 1:200-1:1000
Theoretical MW
55.8 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
TRAF-2 Knockout 293T Cell Lysate

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.05% Sodium Azide
Purity
Protein G purified

Alternate Names for TRAF-2 Antibody (5C2C3)

  • E3 ubiquitin-protein ligase TRAF2
  • EC 6.3.2.-
  • MGC:45012
  • TNF receptor-associated factor 2
  • TRAF2
  • TRAF-2
  • TRAP3
  • TRAP3TRAP
  • tumor necrosis factor type 2 receptor associated protein 3
  • Tumor necrosis factor type 2 receptor-associated protein 3

Background

The protein encoded by this gene is a member of the TNF receptor associated factor (TRAF) protein family. TRAF proteins associate with, and mediate the signal transduction from members of the TNF receptor superfamily. This protein directly interacts with TNF receptors, and forms a heterodimeric complex with TRAF1. This protein is required for TNF-alpha-mediated activation of MAPK8/JNK and NF-kappaB. The protein complex formed by this protein and TRAF1 interacts with the inhibitor-of-apoptosis proteins (IAPs), and functions as a mediator of the anti-apoptotic signals from TNF receptors. The interaction of this protein with TRADD, a TNF receptor associated apoptotic signal transducer, ensures the recruitment of IAPs for the direct inhibition of caspase activation. BIRC2/c-IAP1, an apoptosis inhibitor possessing ubiquitin ligase activity, can unbiquitinate and induce the degradation of this protein, and thus potentiate TNF-induced apoptosis. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of only one transcript has been determined.;

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NB100-56583
Species: Hu, Rb
Applications: WB, Flow, IHC-P, KO
NB100-56508
Species: Hu, Mu, Rt
Applications: WB, Flow, IHC, IHC-P, CyTOF-ready, Flow-CS
NB100-56170
Species: Hu, Bv, Ca
Applications: WB, IHC, IHC-P, IP
NBP2-26506
Species: Hu, Mu, Rt
NB100-56176
Species: Hu, Mu, Rt
Applications: WB, IHC, IHC-P, IP
MAB17761
Species: Hu, Mu, Rt
Applications: WB, ICC
MAB1419
Species: Hu, Rt
Applications: IHC, CyTOF-ready, ICC, ICFlow
NBP1-77077
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P, IF
DDX0131P-100
Species: Hu
Applications: Flow, Func, ICC/IF, IHC, IHC-Fr, IHC-P
H00001513-M01
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC-P
NBP2-37576
Species: Hu, Mu, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
NBP2-67360
Species: Hu, Mu, Rt
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
NB100-317
Species: Hu, Mu
Applications: WB, Flow, ICC/IF, IHC, IHC-P, IP
7270-IL/CF
Species: Hu

Publications for TRAF-2 Antibody (NBP2-61661) (0)

There are no publications for TRAF-2 Antibody (NBP2-61661).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for TRAF-2 Antibody (NBP2-61661) (0)

There are no reviews for TRAF-2 Antibody (NBP2-61661). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for TRAF-2 Antibody (NBP2-61661) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional TRAF-2 Products

Bioinformatics Tool for TRAF-2 Antibody (NBP2-61661)

Discover related pathways, diseases and genes to TRAF-2 Antibody (NBP2-61661). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for TRAF-2 Antibody (NBP2-61661)

Discover more about diseases related to TRAF-2 Antibody (NBP2-61661).
 

Pathways for TRAF-2 Antibody (NBP2-61661)

View related products by pathway.

PTMs for TRAF-2 Antibody (NBP2-61661)

Learn more about PTMs related to TRAF-2 Antibody (NBP2-61661).
 

Research Areas for TRAF-2 Antibody (NBP2-61661)

Find related products by research area.

Blogs on TRAF-2

There are no specific blogs for TRAF-2, but you can read our latest blog posts.

Customers Who Bought This Also Bought

Contact Information

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our TRAF-2 Antibody (5C2C3) and receive a gift card or discount.

Bioinformatics

Gene Symbol TRAF2