TRAF-1 Antibody

Images

 
Western Blot: TRAF-1 Antibody [NB100-56170] - Analysis of TRAF-1 in normal human tissues using this antibody. TRAF-1 is observed at 50-50 kDa. Additional bands of lower molecular weight were seen in some cases, and may ...read more
Immunohistochemistry-Paraffin: TRAF-1 Antibody [NB100-56170] - Formalin-fixed, paraffin-embedded human tissue sections stained for TRAF-1 expression using NB100-56170 at 1:2000. Hematoxylin-eosin counterstain. A, A1: ...read more
Immunohistochemistry-Paraffin: TRAF-1 Antibody [NB100-56170] - Formalin-fixed, paraffin-embedded human lymphoma tissue section stained for TRAF-1 expression using NB100-56170 at 1:2000. Hematoxylin-eosin counterstain. ...read more

Product Details

Summary
Reactivity Hu, Bv, CaSpecies Glossary
Applications WB, IHC, IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

TRAF-1 Antibody Summary

Immunogen
A synthetic peptide corresponding to amino acids between 1 and 50 of human TRAF1 was used as immunogen, GenBank no. NP_005649.1.
Specificity
TRAF1
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRAF1
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:2000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:1000-1:5000
  • Immunoprecipitation 1:50-1:200
Control
TRAF-1 Overexpression Lysate
Publications
Read Publication using
NB100-56170 in the following applications:

  • 1 publication
  • WB
    1 publication

Reactivity Notes

Reacts with Human. 90% sequence identity with bovine and canine proteins.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Neat whole antisera
Preservative
0.02% Sodium Azide
Purity
Unpurified

Alternate Names for TRAF-1 Antibody

  • EBI6
  • EBI6MGC:10353
  • Epstein-Bar virus-induced protein 6
  • Epstein-Barr virus-induced protein 6
  • TNF receptor-associated factor 1
  • TRAF1
  • TRAF-1

Background

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis. This antibody recognizes TRAF1; human TRAF1 is a 416 amino acid protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRAF-1 Antibody (NB100-56170)(1)

We have publications tested in 1 confirmed species: Human.

We have publications tested in 2 applications: IHC-P, WB.


Filter By Application
IHC-P
(1)
WB
(1)
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Filter By Species
Human
(1)
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Product General Protocols

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Video Protocols

WB Video Protocol

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Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol TRAF1
Entrez