Western Blot: TRAF-1 Antibody [NB100-56170] - Analysis of TRAF-1 in normal human tissues using this antibody. TRAF-1 is observed at 50-50 kDa. Additional bands of lower molecular weight were seen in some cases, and may ...read more
Immunohistochemistry-Paraffin: TRAF-1 Antibody [NB100-56170] - Formalin-fixed, paraffin-embedded human tissue sections stained for TRAF-1 expression using NB100-56170 at 1:2000. Hematoxylin-eosin counterstain. A, A1: ...read more
Immunohistochemistry-Paraffin: TRAF-1 Antibody [NB100-56170] - Formalin-fixed, paraffin-embedded human lymphoma tissue section stained for TRAF-1 expression using NB100-56170 at 1:2000. Hematoxylin-eosin counterstain. ...read more
Hu, Bv, CaSpecies Glossary
WB, IHC, IHC-P, IP
This product is unpurified. The exact concentration of antibody is not quantifiable.
Reacts with Human. 90% sequence identity with bovine and canine proteins.
Alternate Names for TRAF-1 Antibody
Epstein-Bar virus-induced protein 6
Epstein-Barr virus-induced protein 6
TNF receptor-associated factor 1
The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor superfamilies and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis. This antibody recognizes TRAF1; human TRAF1 is a 416 amino acid protein.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.