TRAF-3 Antibody

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Immunohistochemistry-Paraffin: TRAF-3 Antibody - Unpurified [NB100-56176] - Analysis of formalin fixed paraffin-embedded (FFPE) human tonsil using this at 1:4000 on a Bond Rx autostainer (Leica Biosystems). The assay ...read more

Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, IHC, IHC-P, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated

Order Details

TRAF-3 Antibody Summary

Immunogen
A recombinant protein fragment corresponding to the cytoplasmic end of human TRAF3 (amino acids 341-568) was used as immunogen, GenBank no. GenBank no. gi|22027616|ref|NP_003291.2|.
Specificity
TRAF3
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TRAF3
Purity
Unpurified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:1000-1:2000
  • Immunohistochemistry 1:4000
  • Immunohistochemistry-Paraffin 1:4000
  • Immunoprecipitation 1:50-1:200
Control
TRAF-3 Overexpression Lysate
TRAF-3 Knockout HeLa Cell Lysate
Publications
Read Publication using NB100-56176.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Whole antisera
Preservative
0.02% Sodium Azide
Purity
Unpurified

Alternate Names for TRAF-3 Antibody

  • CAP1
  • CAP-1CD40 receptor associated factor 1
  • CD40 associated protein 1
  • CD40 binding protein
  • CD40 receptor-associated factor 1
  • CD40-binding protein
  • CD40bp
  • CRAF1
  • CRAF1CAP1
  • LAP1
  • LAP1CD40BP
  • LMP1-associated protein 1
  • TNF receptor-associated factor 3
  • TRAF3
  • TRAF-3

Background

The TRAF (TNF receptor-associated factor) family is a group of adapter proteins (TRAFs 1-6) that link a wide variety of cell surface receptors to diverse signaling cascades leading to the activation of NF-kB and mitogen-activated protein kinases (reviewed in Chung et al, 2002). TRAFs are major signal transducers for both the TNF and IL- 1/TLR receptor super families and collectively play important functions in both adaptive and innate immunity. The carboxy-terminal region of TRAFs is required for self-association and interaction with receptor cytoplasmic domains following ligand-induced oligomerization. TRAFs interact with a variety of proteins that regulate receptor-induced cell death or survival, and TRAF-mediated signaling can promote cell survival or interfere with death receptor-induced apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for TRAF-3 Antibody (NB100-56176)(1)

We have publications tested in 1 application: WB.


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Video Protocols

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Control Lysate(s)

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Bioinformatics

Gene Symbol TRAF3
Entrez