Human Osteoprotegerin/TNFRSF11B DuoSet ELISA, 15 Plate



Product Details

Reactivity HuSpecies Glossary
Applications ELISA

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Human Osteoprotegerin/TNFRSF11B DuoSet ELISA, 15 Plate Summary

Assay Type
Solid Phase Sandwich ELISA
See PDF Datasheet for details
See PDF Datasheet for details
Spike Recovery
See PDF Datasheet for details
Sample Volume
See PDF Datasheet for details


Application Notes
No significant interference observed with available related molecules.
Read Publications using
DY805 in the following applications:

Packaging, Storage & Formulations

Store the unopened product at 2 - 8 °C. Do not use past expiration date.


This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Human Osteoprotegerin/TNFRSF11B DuoSet ELISA, 15 Plate

  • OCIF
  • OCIFMGC29565
  • OPG
  • OPGtumor necrosis factor receptor superfamily member 11B
  • Osteoclastogenesis inhibitory factor
  • Osteoprotegerin
  • TR1
  • tumor necrosis factor receptor superfamily, member 11b


Osteoprotegerin (OPG), also known as OCIF and TNFRSF11B, is a secreted TNF superfamily receptor that regulates bone density. OPG is widely expressed and constitutively released as a homodimer by mesenchymal stem cells, fibroblasts, and endothelial cells. OPG functions as a decoy receptor for TRANCE/RANK L and TRAIL. OPG regulates the cell surface expression of TRANCE and its ability to stimulate osteoclastogenesis. Dysregulation of OPG/TRANCE interactions can lead to juvenile Paget’s disease, osteoporosis, bone loss, and vascular calcification.

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Publications for Osteoprotegerin/TNFRSF11B (DY805)(82)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 1 application: ELISA Capture.

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Showing Publications 1 - 10 of 82. Show All 82 Publications.
Publications using DY805 Applications Species
KEC Blokland, M Nizamoglu, H Habibie, T Borghuis, M Schuliga, BN Melgert, DA Knight, CA Brandsma, SD Pouwels, JK Burgess Substrate stiffness engineered to replicate disease conditions influence senescence and fibrotic responses in primary lung fibroblasts Frontiers in Pharmacology, 2022-11-03;13(0):989169. 2022-11-03 [PMID: 36408252] (Human) Human
T Nicholson, L Davis, ET Davis, M Newton Ede, A Scott, SW Jones e-Cigarette Vapour Condensate Reduces Viability and Impairs Function of Human Osteoblasts, in Part, via a Nicotine Dependent Mechanism Toxics, 2022-08-28;10(9):. 2022-08-28 [PMID: 36136470] (Human) Human
R Galla, S Ruga, S Aprile, S Ferrari, A Brovero, G Grosa, C Molinari, F Uberti New Hyaluronic Acid from Plant Origin to Improve Joint Protection-An In Vitro Study International Journal of Molecular Sciences, 2022-07-23;23(15):. 2022-07-23 [PMID: 35897688] (Human) Human
J Jiang, L Röper, S Alageel, U Dornseifer, AF Schilling, E Hadjipanay, HG Machens, P Moog Hypoxia Preconditioned Serum (HPS) Promotes Osteoblast Proliferation, Migration and Matrix Deposition Oncogene, 2022-07-07;10(7):. 2022-07-07 [PMID: 35884936] (Human) Human
HJ Kim, MS Park, A Joo, S Kang, S Eum, Y Chang, TJ Song Plasma osteoprotegerin level is associated with hemorrhagic transformation in stroke patients who underwent endovascular thrombectomy Clinical neurology and neurosurgery, 2022-05-25;219(0):107305. 2022-05-25 [PMID: 35653867] (Human) Human
MS Park, JH Park, A Joo, Y Chang, TJ Song The association of plasma osteoprotegerin levels and functional outcomes post endovascular thrombectomy in acute ischemic stroke patients: a retrospective observational study PeerJ, 2022-05-03;10(0):e13327. 2022-05-03 [PMID: 35529501] (Human) Human
S Passaponti, L Ermini, G Acconci, FM Severi, R Romagnoli, S Cutrupi, M Clerico, G Guerrera, F Ietta Rank-Rankl-Opg Axis in Multiple Sclerosis: The Contribution of Placenta Cells, 2022-04-15;11(8):. 2022-04-15 [PMID: 35456036] (Human) Human
S Hinkelmann, AH Springwald, S Schulze, U Hempel, F Mitrach, C Wölk, MC Hacker, M Schulz-Sie Mineralizing Gelatin Microparticles as Cell Carrier and Drug Delivery System for siRNA for Bone Tissue Engineering Pharmaceutics, 2022-02-28;14(3):. 2022-02-28 [PMID: 35335924] (Human) Human
JW Kennedy, PM Tsimbouri, P Campsie, S Sood, PG Childs, S Reid, PS Young, DRM Meek, CS Goodyear, MJ Dalby Nanovibrational stimulation inhibits osteoclastogenesis and enhances osteogenesis in co-cultures Scientific Reports, 2021-11-23;11(1):22741. 2021-11-23 [PMID: 34815449] (Human) Human
MS Park, Y Chang, KH Kim, JH Park, TJ Song Plasma osteoprotegerin levels are associated with the presence and burden of cerebral small vessel disease in patients with acute ischemic stroke Clinical neurology and neurosurgery, 2021-10-28;210(0):107010. 2021-10-28 [PMID: 34752988] (Human) Human
Show All 82 Publications.

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Gene Symbol TNFRSF11B