TLR6 Antibody


Western Blot: TLR6 Antibody [NB110-93544] - Detection of TLR6 in Jurkat whole cell extract using NB110-93544.

Product Details

Reactivity Hu, Mu, Rt, PmSpecies Glossary
Applications WB
1 mg/ml

Order Details

Available Conjugates
Catalog# & Conjugate Size Price

TLR6 Antibody Summary

Synthetic peptide made to a C-terminal portion of the human TLR6 protein (within residues 700-796). [Swiss-Prot# Q9Y2C9]
Cell membrane; Single-pass type I membrane protein
Predicted Species
Sheep (92%)
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris-citrate/phosphate, pH 7-8
0.1% Sodium Azide
1 mg/ml
Immunogen affinity purified


Application Notes
This TLR6 antibody is useful for Western blot, where a band is seen at ~96 kDa.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
96 kDa

Reactivity Notes

Human, mouse, primate and rat. Immunogen sequence has 92% homology to sheep.

Alternate Names for TLR6 Antibody

  • CD286 antigen
  • CD286
  • toll-like receptor 6


TLR6 (toll-like receptor 6, also called CD286) belongs the family of TLRs which are membrane receptors with potential of acting as gatekeepers of the innate immunity through recognizing microbial components and initiating activation of an adequate immune response. Localized in cell membrane as well as in cytoplasmic vesicle/phagosome membrane as single-pass type I membrane protein, TLR6 is expressed in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. TLR6 participates in the innate immune response to Gram-+ve bacteria and fungi. It specifically recognize diacylated/triacylated lipopeptides, and has the ability to recognize mycoplasmal macrophage-activating lipopeptide-2kD (MALP-2), soluble tuberculosis factor, phenol-soluble modulin and Borrelia burgdorferi outer surface protein A lipoprotein (OspA-L) cooperatively with TLR2. It acts via MYD88 and TRAF6, leading to NFkB activation, cytokine secretion and inflammatory response. Moreover, it has been shown to bind MYD88 and dimerize with TLR2, wherein TLR6- TLR2 heterodimers recognize a large number of lipidcontaining molecules and transducers inflammatory signalling in a variety of cell type.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

View specific protocols for TLR6 Antibody (NB110-93544): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

DyLight 405 Labeled NB110-93544V
FITC Labeled NB110-93544F

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Blogs on TLR6.

Exploring Various Studies on TLR6 Expression
The protein TLR6 is one member of the large Toll-like receptor (TLR) family, which governs the activation of the innate immunity system and pathogen recognition in cells. The TLR family is highly conserved from Drosophila to humans, and all the family...  Read full blog post.

Contact Information

Product PDFs


Gene Symbol TLR6

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