TAZ/WWTR1 Antibody - BSA Free


Western Blot: TAZ/WWTR1 Antibody [NB110-58359] - Detection of TAZ on HEK 293 cell lysate using NB110-58359.
Immunocytochemistry/ Immunofluorescence: TAZ/WWTR1 Antibody [NB110-58359] - Detection of TAZ (Green) in HepG2 cells using NB110-58359. Nuclei (Blue) are counterstained with Hoecsht 33258.
Immunohistochemistry-Paraffin: TAZ/WWTR1 Antibody [NB110-58359] - IHC analysis of formalin fixed paraffin-embedded (FFPE) human kidney using TAZ/WWTR1 antibody at 1:500 on a Bond Rx autostainer (Leica Biosystems). The ...read more
Simple Western: TAZ/WWTR1 Antibody [NB110-58359] - Simple Western lane view shows a specific band for TAZ in 0.5 mg/ml of HeLa lysate. This experiment was performed under reducing conditions using the 12-230 kDa ...read more

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, Simple Western, ChIP, ICC/IF, IHC, IHC-P, IP, PLA
BSA Free
1.0 mg/ml

Order Details

TAZ/WWTR1 Antibody - BSA Free Summary

Synthetic peptides made to the human TAZ protein. These peptides were selected for the lack of homology to YAP protein. [UniProt# Q9GZV5]
Nuclear and cytoplasmic. Concentrates along specific portions of the plasma membrane, and accumulates in punctate nuclear bodies.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.


  • Chromatin Immunoprecipitation
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:500
  • Immunohistochemistry-Paraffin 1:500
  • Immunoprecipitation 1:100
  • Proximity Ligation Assay
  • Simple Western 1:100
  • Western Blot 1:1000-1:5000
Application Notes
This TAZ Antibody is useful for Immunocytochemistry/Immunofluorescence, Immunoprecipitation and Western blot. Use in chromatin immunoprecipitation and Immunohistochemistry-paraffin reported in scientific literature (PMID 25587023). Use in Proximity Ligation Assay reported in scientific literature (PMID: 25587023).

In Simple Western only 10 - 15 uL of the recommended dilution is used per data point. Separated by Size-Wes, Sally Sue/Peggy Sue.
293 Whole Cell Lysate
Human Kidney Whole Tissue Lysate (Adult Whole Normal)
TAZ/WWTR1 Overexpression Lysate
Reviewed Applications
Read 1 Review rated 3
NB110-58359 in the following applications:

Read Publications using
NB110-58359 in the following applications:

  • 4 publications
  • 3 publications
  • 2 publications
  • IP
    3 publications
  • WB
    8 publications

Reactivity Notes

Human, Mouse and Rat.

Packaging, Storage & Formulations

Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
0.02% Sodium Azide
1.0 mg/ml
Immunogen affinity purified

Alternate Names for TAZ/WWTR1 Antibody - BSA Free

  • FLJ27004
  • FLJ45718
  • TAZ
  • TAZDKFZp586I1419
  • transcriptional co-activator with PDZ-binding motif
  • Transcriptional coactivator with PDZ-binding motif
  • WW domain containing transcription regulator 1
  • WW domain-containing transcription regulator protein 1
  • WWTR1


TAZ (transcriptional co-activator with PDZ-binding motif) was identified as a binding partner of 14-3-3 family of proteins which contains seven homologous proteins with ability to bind phosphorylated serine with certain sequence motifs, thereby involving in diverse cellular functions such as differentiation, cell cycle progression and apoptosis via their interaction with diverse intracellular phosphoproteins involved in signaling networks. TAZ is homologous to YAP and displays transcriptional co-activator function via interaction with PPXY-containing transcriptional factors through its WW domain. Several transcriptional factors such as Runx/PEBP2, AP2, C/EBP, c-Jun, Krox-20, Krox-24, MEF2B, NF-E2, Oct-4 and p73 containing proline-rich PPXY motif have been proposed as TAZ's interacting partners. TAZ is also a major target of the Hippo core kinase cascade which regulates organ size control as well as stem cell properties by governing cell proliferation and apoptosis processes. Hippo mediated phosphorylation of YAP and TAZ leads to their sequestration into the cytoplasm by interaction with 14-3-3 proteins and ubiquitination-dependent proteosomal degradation, thereby governing its distribution, protein levels and functionality. TAZ interacts primarily with transcriptional factors TEAD1-4 (TEADs) and activates expression of target genes such as CTGF, IGFBP3, ITGB2, Birc5/Survivin, Gli2, and Axl.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Applications: ICC/IF, IHC, IHC-P, WB
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Applications: BA
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Publications for TAZ/WWTR1 Antibody (NB110-58359)(15)

We have publications tested in 3 confirmed species: Human, Mouse, Rat.

We have publications tested in 5 applications: ChIP, ICC/IF, IHC-P, IP, WB.

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Showing Publications 1 - 10 of 15. Show All 15 Publications.
Publications using NB110-58359 Applications Species
Das A, Adhikary S, Roy Chowdhury A, Barui A Leveraging substrate stiffness to promote stem cell asymmetric division via mechanotransduction-polarity protein axis and its Bayesian regression analysis Rejuvenation research Mar 22 2022 [PMID: 35316074] (ICC/IF) ICC/IF
Hwang JH, Kim KM, Oh HT et al. TAZ links exercise to mitochondrial biogenesis via mitochondrial transcription factor A Nature communications Feb 3 2022 [PMID: 35115527] (ChIP, Mouse) ChIP Mouse
Luu A, Yao Z, Ramachandran S Et al. A CRISPR Activation Screen Identifies an Atypical Rho GTPase That Enhances Zika Viral Entry Viruses Oct 20 2021 [PMID: 34834920]
Van Sciver N, Ohashi M, Pauly NP Et al. Hippo signaling effectors YAP and TAZ induce Epstein-Barr Virus (EBV) lytic reactivation through TEADs in epithelial cells PLoS pathogens Aug 1 2021 [PMID: 34339458] (WB, Human) WB Human
Li W, Zhao J, Wang J et al. ROCK-TAZ signaling axis regulates mechanical tension-induced osteogenic differentiation of rat cranial sagittal suture mesenchymal stem cells J. Cell. Physiol. Jan 22 2020 [PMID: 31970784] (IP, WB, Rat) IP, WB Rat
Kegelman CD, Coulombe JC, Jordan KM et al. YAP and TAZ Mediate Osteocyte Perilacunar/Canalicular Remodeling J. Bone Miner. Res. 2019 Oct 14 [PMID: 31610061] (Mouse) Mouse
Hwang JH, Kim AR, Kim KM et al. TAZ couples Hippo/Wnt signalling and insulin sensitivity through Irs1 expression. Nat Commun Jan 24 2019 [PMID: 30679431] (ChIP, Mouse) ChIP Mouse
Yu B, Huo L, Liu Y et al. PGC-1a Controls Skeletal Stem Cell Fate and Bone-Fat Balance in Osteoporosis and Skeletal Aging by Inducing TAZ. Cell Stem Cell. Jul 3 2018 [PMID: 30017591] (IHC-P, ICC/IF, WB, Mouse) IHC-P, ICC/IF, WB Mouse
Wu LMN, Deng Y, Wang J, Zhao C. Programming of Schwann Cells by Lats1/2-TAZ/YAP Signaling Drives Malignant Peripheral Nerve Sheath Tumorigenesis. Cancer Cell. 2018 Feb 12 [PMID: 29438698] (Human) Human
Deng Y, Wu LMN, Bai S et al. A reciprocal regulatory loop between TAZ/YAP and G-protein Gas regulates Schwann cell proliferation and myelination. Nat Commun Apr 26 2017 [PMID: 28443644] (WB, Human) WB Human
Show All 15 Publications.

Review for TAZ/WWTR1 Antibody (NB110-58359) (1) 31

Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Human.

Reviews using NB110-58359:
Filter by Applications
Western Blot
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Images Ratings Applications Species Date Details
Western Blot TAZ/WWTR1 NB110-58359
reviewed by:
Verified Customer
Western Blot Human 11/06/2013


ApplicationWestern Blot
Sample TestedHEK293T cell lysate

Product General Protocols

Video Protocols

WB Video Protocol
ChIP Video Protocol
ChIP Webinar
ICC/IF Video Protocol

FAQs for TAZ/WWTR1 Antibody (NB110-58359). (Showing 1 - 4 of 4 FAQs).

  1. I want to know which TAZ primary antibody is best produced for WB (human and mouse)!
    • I would recommend this TAZ antibody: NB110-58359. This is also comes in a sample size.
  2. We have an inquiry for your product #NB110-58359, TAZ Antibody. Our customer would like to try this product with rat cells lysate. Could you please let me know if you have data image of rat cells lysate can provide?
    • This antibody has been validated and is therefore guaranteed for use in human, rat and mouse in the following applications: Western blot, Immunoprecipitation and ICC/IF. We do not currently have a WB image that we can share however rat is one of the guaranteed species.
  3. Our customer was interested in the TAZ Antibody (Cat.NB110-58359). Could you please help to confirm if it has been tested with rat cells?
    • The TAZ antibody, NB110-58359, has been tested and validated for use in rat and is therefore guaranteed. Our 100% guarantee covers all of our products for the listed species and applications.
  4. I am looking for a WWTR1 antibody and NB110-58359 looks like the best one. I wonder if you guys can provide me the target sequence information of the antibody?
    • WWTR1 antibody (NB110-58359) is generated against residues 178-197 of WWTR1 (immunogen accession number Q9GZV5). The exact immunogen sequence for this antibody is: CPQRSMAVSQPNLVMNHQHQQ

Control Lysate(s)

Secondary Antibodies


Isotype Controls

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Recent Reviews


Verified Customer
Application: Western Blot
Species: Human


Gene Symbol WWTR1