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Synaptopodin, a prolin-rich actin-binding protein with 2 binding sites for actin, represents a new class of actin-binding proteins which has first been localized in podocytes and a subset of telencephalic postsynaptic densities. In human tissue synaptopodin has a molecular weight of 73.7 kD and pI of 9.38 (calculated from sequence data); in mouse the corresponding data are 74 kD, pI 9.27. In SDS-PAGE the antigen appears as 100 kD polypeptide in brain and 110 kD polypeptide in kidney (the difference might be attributed to posttranslational modifications).
![Immunohistochemistry Synaptopodin Antibody (918842) [Unconjugated]](http://images.novusbio.com/fullsize/antibody/Synaptopodin_MAB8977_Immunohistochemistry_19159.jpg)
![Immunocytochemistry/ Immunofluorescence Synaptopodin Antibody (918842) [Unconjugated]](http://images.novusbio.com/fullsize/mab8977_human-synaptopodin-mab-clone-918842-41202412505383.jpg)
![Immunocytochemistry/ Immunofluorescence Synaptopodin Antibody (918842) [Unconjugated]](http://images.novusbio.com/fullsize/mab8977_human-synaptopodin-mab-clone-918842-41202412512688.jpg)
![Immunocytochemistry/ Immunofluorescence Synaptopodin Antibody (918842) [Unconjugated]](http://images.novusbio.com/fullsize/mab8977_human-synaptopodin-mab-clone-918842-41202412505374.jpg)
