STEAP1 Antibody - BSA Free

Images

 
Western Blot: STEAP1 Antibody [NBP1-76821] - Human spleen tissue lysate with STEAP1 antibody at (A) 1 and (B) 2 ug/mL.
Immunohistochemistry-Paraffin: STEAP1 Antibody [NBP1-76821] - Human spleen tissue with STEAP1 antibody at 2.5 ug/ml.

Product Details

Summary
Reactivity Hu, Mu, Rt, PoSpecies Glossary
Applications WB, ELISA, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1 mg/ml

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Catalog# & Formulation Size Price

STEAP1 Antibody - BSA Free Summary

Immunogen
Antibody was raised against a 18 amino acid synthetic peptide from near the carboxy terminus of human STEAP1. The immunogen is located within the last 50 amino acids of STEAP1. Amino Acid Squence: CLRKKILKIRHGWEDVTK
Specificity
This STEAP1 antibody does not cross-react with other STEAP proteins.
Predicted Species
Porcine (94%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
STEAP1
Purity
Peptide affinity purified
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Applications/Dilutions

Dilutions
  • ELISA 1:100-1:2000
  • Immunohistochemistry 2.5 ug/ml
  • Immunohistochemistry-Paraffin 2.5 ug/ml
  • Western Blot 1-2 ug/ml
Control Peptide
STEAP1 Peptide (NBP1-76821PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Peptide affinity purified

Alternate Names for STEAP1 Antibody - BSA Free

  • EC 1.16.1.-
  • PRSS24
  • PRSS24MGC19484
  • six transmembrane epithelial antigen of the prostate 1
  • six transmembrane epithelial antigen of the prostate
  • Six-transmembrane epithelial antigen of prostate 1
  • STEAP1
  • STEAPmetalloreductase STEAP1

Background

The six-transmembrane epithelial antigen of prostate 1 (STEAP1) was the first member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. The normal function of STEAP is still uncertain; unlike other members of the STEAP family, STEAP1 does not promote iron or copper reduction or uptake and lacks the FNO-like reductase domain critical for activity. However, its expression is highly increased in multiple cancer cell lines, including prostate, bladder, colon, and ovarian cancers. Supporting this is evidence that STEAP1 peptides can be used to stimulate CD8+ T cells from healthy donors, enabling them to recognize STEAP1-positive human tumor cells, suggesting that STEAP1 may a potential target for cancer immunotherapy. At least three isoforms of STEAP1 are known to exist. This STEAP1 antibody does not cross-react with other STEAP proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Video Protocols

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol STEAP1
Uniprot