WB: Approx. 50-55 kDa band observed in human adipose lysates (calculated MW of 52.0 kDa band according to NP_078912.2). In transfected HEK293 transiently expressing human Dudulin4 a band of approx. 52 kDa is observed. This band is not observed in the non-transfected HEK293. IP reactivity per customer review.
52 kDa. Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
0.02% Sodium Azide
Immunogen affinity purified
Alternate Names for STAMP2/STEAP4 Antibody
Six-transmembrane epithelial antigen of prostate 4
SixTransMembrane protein of prostate 2
STEAP family member 4
TIARPsix transmembrane prostate protein 2
Tumor necrosis factor, alpha-induced protein 9metalloreductase STEAP4
tumor necrosis-alpha-induced adipose-related protein
STEAP4 is a member of a family of metalloreductases identified as cell-surface antigens in prostate tissue. It is similar to two other members of the STEAP family, STEAP2 and STEAP3. STEAP4 promotes the reduction of both iron (Fe3+ to Fe2+) and copper (Cu2+ to Cu1+). STEAP4 is highly expressed in placenta, lung, heart and prostate tissues. Furthermore, it is over expressed in prostate cancer cells compared to normal prostate cells. STEAP4 may have a role in cell proliferation and prostrate cancer progression since over expression of STEAP4 in prostate cells significantly increases cell growth and colony formation. At least two isoforms of this protein are known to exist.
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.
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