STEAP1 Products

Description

Six-transmembrane epithelial antigen of the prostate (STEAP) is expressed predominantly in human prostate tissue and in other common malignancies including prostate, bladder, colon, and ovarian carcinomas, and in Ewing's sarcoma, suggesting that it could function as an almost universal tumor antigen. Immunohistochemical analysis indicated STEAP-1 localization at cell-cell junctions of the secretory epithelium of prostate and prostate cancer cells. The favorable expression profiling of STEAP-1 in normal and cancer tissues suggested its potential use as a target for immunotherapy. Clone J2D2, is derived from hybridization of mouse F0 myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human STEAP1 protein.

Bioinformatics

Entrez	26872 Human
Uniprot	AAH11802 Human EAL24166 Human NP_036581 Human NP_036581.1 Human
Product By Gene ID	26872
Alternate Names	EC 1.16.1.- PRSS24MGC19484 six transmembrane epithelial antigen of the prostate 1 six transmembrane epithelial antigen of the prostate Six-transmembrane epithelial antigen of prostate 1 STEAPmetalloreductase STEAP1

Research Areas for STEAP1

Find related products by research area and learn more about each of the different research areas below.

Cancer