SR-AI/MSR Antibody - BSA Free

Images

 
Western Blot: SR-AI/MSR Antibody [NBP1-00092] - Detection of Macrophage Scavenger Receptor I (MSR1) protein in the lysate of human liver.
Immunocytochemistry/ Immunofluorescence: SR-AI/MSR Antibody [NBP1-00092] - The MSR antibody was tested in Raw cells at a 1:250 dilution against DyLight 488 (Green). Alpha-tubulin and nuclei were counterstained against ...read more
Immunohistochemistry-Frozen: SR-AI/MSR Antibody - BSA Free [NBP1-00092] - Immune labeling of non-parenchymal liver cell (NPC) cultures for selected SRs and C-type lectins. NPCs from the 25-45% interface on the Percoll ...read more
Flow Cytometry: SR-AI/MSR Antibody [NBP1-00092] - A surface stain was performed on Raw264.7 cells with SR-AI/MSR Antibody NBP1-00092R (blue) and a matched isotype control (orange). Cells were incubated in an antibody ...read more

Product Details

Summary
Reactivity Hu, Mu, Rt, Bv, Ca, Eq, PmSpecies Glossary
Applications WB, Flow, ICC/IF, IHC, IHC-Fr, IHC-P, PLA
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Format
BSA Free
Concentration
1.00 mg/ml

Order Details

SR-AI/MSR Antibody - BSA Free Summary

Immunogen
Synthetic peptide made to an internal portion of human Macrophage Scavenger Receptor I (within residues 400-450). [Swiss-Prot: P21757]
Localization
Membrane; Single-pass type II membrane protein.
Predicted Species
Rat (92%), Canine (100%), Primate (93%), Equine (100%), Bovine (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
MSR1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Flow Cytometry 2-5 ug/million cells
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Immunohistochemistry-Paraffin
  • Proximity Ligation Assay
  • Western Blot 0.5 ug/ml
Application Notes
In Western blot, a band is seen ~50 kDa. Use in proximity ligation assay reported in scientific literature (PMID: 28338748). Use in Immunohistochemistry reported in scientific literature (PMID: 26358193).
Theoretical MW
50 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Control
Human Liver Whole Tissue Lysate (Adult Whole Normal)
SR-AI/MSR Overexpression Lysate
Control Peptide
SR-AI/MSR Peptide (NBP1-00092PEP)
Reviewed Applications
Read 2 Reviews rated 5
using
NBP1-00092 in the following applications:

Publications
Read Publications using
NBP1-00092 in the following applications:

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS and 30% Glycerol
Preservative
0.1% Sodium Azide
Concentration
1.00 mg/ml
Purity
Immunogen affinity purified

Alternate Names for SR-AI/MSR Antibody - BSA Free

  • CD204 antigen
  • CD204
  • Macrophage acetylated LDL receptor I and II
  • macrophage scavenger receptor 1
  • macrophage scavenger receptor type III
  • MSR1
  • phSR1
  • phSR2
  • SCARA1
  • SCARA1macrophage scavenger receptor types I and II
  • Scavenger receptor class A member 1
  • scavenger receptor class A, member 1
  • SR-A
  • SRAI
  • SR-AI

Background

Macrophage Scavenger Receptor I (MSR1, also called CD204 or scavenger receptor A) belongs to scavenger receptor A family and represents phagocytic pattern-recognition receptors (PRRs) expressed predominantly on macrophages and dendritic cells. MSR1 is a single-pass type II membrane glycoprotein capable of binding to a wide range of polyanionic ligands (e.g., modified low density lipoproteins, pathogen-derived molecules), and is implicated in the pathologic deposition of cholesterol in arterial walls during atherogenesis, innate immune response as well as Alzheimer's disease. MSR1 mediates the endocytosis of a diverse group of macromolecules including modified LDLs, and scavenger receptors MSR1, CD36 and LOX-1 are three main receptors for oxidized LDL on macrophage membrane wherein MSR1/CD36 account for more than 9/10 of the lipid accumulation in macrophages exposed to oxidized LDL. Defects in MSR1 have also been linked to prostate cancer and Barrett esophagus (BE).

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for SR-AI/MSR Antibody (NBP1-00092)(6)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: ICC/IF, IF/IHC, IHC-Fr, PLA, WB.


Filter By Application
ICC/IF
(1)
IF/IHC
(2)
IHC-Fr
(1)
PLA
(1)
WB
(1)
All Applications
Filter By Species
Human
(1)
Mouse
(4)
All Species

Reviews for SR-AI/MSR Antibody (NBP1-00092) (2) 52

Average Rating: 5
(Based on 2 reviews)
We have 2 reviews tested in 1 species: Canine.

Reviews using NBP1-00092:
Filter by Applications
ICC
(2)
All Applications
Filter by Species
Canine
(2)
All Species
Images Ratings Applications Species Date Details
Immunocytochemistry SR-AI/MSR NBP1-00092
Enlarge
5
reviewed by:
A G
ICC Canine 06/13/2017
View

Summary

ApplicationImmunocytochemistry
Sample TestedDog blood cells on slide
SpeciesCanine
Lotb-9
Immunocytochemistry SR-AI/MSR NBP1-00092
Enlarge
5
reviewed by:
Verified Customer
ICC Canine 03/24/2017
View

Summary

ApplicationImmunocytochemistry
Sample TestedPeripheral blood leukocytes
SpeciesCanine
LotB9

Product General Protocols

View specific protocols for SR-AI/MSR Antibody (NBP1-00092): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for SR-AI/MSR Antibody (NBP1-00092) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for SR-AI/MSR Antibody (NBP1-00092)

Discover related pathways, diseases and genes to SR-AI/MSR Antibody (NBP1-00092). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on SR-AI/MSR

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Recent Reviews

5
5
2
4
0
3
0
2
0
1
0

A G
06/13/2017
Application: ICC
Species: Canine

Verified Customer
03/24/2017
Application: ICC
Species: Canine

Bioinformatics

Gene Symbol MSR1