SR-AI/MSR Products

Description

Macrophage scavenger receptors (MSR) are membrane glycoproteins that mediate the recognition and uptake of a variety of macromolecules, including modified lipoproteins, advanced glycation end (AGEs) products and amyloid b-protein (Abeta). While the normal role of MSR is associated with cell adhesion and host defense mechanisms, it also has been implicated in the development of atherosclerosis and Abeta deposition in Alzheimer's disease (AD).

In cell cultures, macrophage scavenger receptor has been shown to mediate adhesion of macrophages and other cell lines to tissue culture plastic. MSR1 antibodies are useful for research on atherosclerosis, Alzheimer's disease, and host defense.

Bioinformatics

Entrez	20288 Mouse 4481 Human 498638 Rat
Uniprot	NM_138715 Human NP_002436 Human NP_619729 Human NP_619730 Human P21757 Human
Product By Gene ID	4481
Alternate Names	CD204 antigen CD204 Macrophage acetylated LDL receptor I and II macrophage scavenger receptor 1 macrophage scavenger receptor type III phSR1 phSR2 SCARA1macrophage scavenger receptor types I and II Scavenger receptor class A member 1 scavenger receptor class A, member 1 SR-A

Research Areas for SR-AI/MSR

Find related products by research area and learn more about each of the different research areas below.

Adaptive Immunity
Cancer
Immunology
Innate Immunity
Lipid and Metabolism
Neuroscience
Prostate Cancer