SNX27 Antibody


Western Blot: SNX27 Antibody [NBP1-45282] - WB analysis of SNX27 in human liver.
Immunocytochemistry/ Immunofluorescence: SNX27 Antibody [NBP1-45282] - Detection of SNX27 (Green) in Hela cells using NBP1-45282. Nuclei (Blue) are counterstained using Hoechst 33258.
Immunohistochemistry: SNX27 Antibody [NBP1-45282] - IHC analysis of SNX27 in mouse bladder using DAB with hematoxylin counterstain.

Product Details

Reactivity Hu, Mu, Rt, BvSpecies Glossary
Applications WB, ICC/IF, IHC, IHC-P
1 mg/ml

SNX27 Antibody Summary

Synthetic peptide made to an internal portion of human SNX27 (within residues 150-200). [Swiss-Prot# Q96L92]
Cytoplasm cytosol. Early endosome. Note: In T lymphocytes, recruited from the cytosol to sorting endosomes by phosphoinositide-3-kinase products.
Predicted Species
Rat (94%), Bovine (94%). Backed by our 100% Guarantee.
Immunogen affinity purified
Innovator's Reward
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  • Western Blot 0.5 ug/ml
  • Immunocytochemistry/Immunofluorescence 1:50-1:200
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
Application Notes
This SNX27 antibody is useful for Immunocytochemistry/Immunofluorescence, Immunohistochemistry on paraffin-embedded sections and Western blot, where a band is seen at ~64 kDa. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
64 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
Brain Lysate (NB820-59657)
Brain Lysate (NB820-59177)
Control Peptide
SNX27 Peptide (NBP1-45282PEP)

Reactivity Notes

Human and mouse. Immunogen sequence has 94% identity to rat and bovine.

Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
PBS and 30% Glycerol
0.1% Sodium Azide
1 mg/ml
Immunogen affinity purified

Alternate Names for SNX27 Antibody

  • KIAA0488MGC126873
  • methamphetamine-responsive transcript 1
  • MGC126871
  • MGC20471
  • MRT1
  • MY014
  • sorting nexin family member 27
  • sorting nexin-27


SNX27 belongs to SNX family of proteins which are unified by the presence of a phox domain, a phospholipid-binding motif, and are involved in intracellular sorting as well as trafficking. SNX27 was initially discovered in neocortex of rat as a developmentally regulated psychostimulant-inducible novel gene, which was named mrt1 (methamphetamine-responsive transcript 1), having two splice forms mrt1a (SNX27a) and mrt1b (SNX27b) that vary only in their C-terminal ends. In SNX family, SNX27 is the only SNX member containing a PDZ domain and it interact with the PDZ-bm of a few membrane proteins through its PDZ domain to regulate their intracellular sorting. SNX27 modulates the early endosomal trafficking of 5-HT4(a)R [5-hydroxytryptamine type-4(a) receptor], Kir3 (G protein-gated potassium) channels, NR2C (N-methyl-D-aspartate receptor 2C) etc., and has also been suggested to facilitate efficient recycling of beta2AR/beta2-adrenoreceptor to the plasma membranes.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor 405 Labeled NBP1-45282AF405
Alexa Fluor 488 Labeled NBP1-45282AF488
Alexa Fluor 647 Labeled NBP1-45282AF647
Alexa Fluor 700 Labeled NBP1-45282AF700
Biotin Labeled NBP1-45282B
DyLight 405 Labeled NBP1-45282V
DyLight 488 Labeled NBP1-45282G
DyLight 550 Labeled NBP1-45282R
DyLight 650 Labeled NBP1-45282C
FITC Labeled NBP1-45282F
HRP Labeled NBP1-45282H

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SNX27 NBP1-45282

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Blogs on SNX27.

Spotlight on SNX27 Antibodies
Sorting Nexin Family Member 27 (SNX27) binds the cell membrane to regulate endocytic vesicular and protein trafficking. SNX27 has also been shown to play a key role in the endocytic recycling pathway, whereby internalized membrane proteins and lipids...  Read full blog post.

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Gene Symbol SNX27