SMC2 Antibody (E1M)

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Western Blot: SMC2 Antibody (E1M) [NBP2-66582] - HeLa cell lysate.

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB
Clone
E1M
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

Order Details

SMC2 Antibody (E1M) Summary

Immunogen
Hybridoma produced by the fusion of splenocytes from mice immunized with recombinant protein corresponding to amino acids 523-768 of human SMC2 and mouse myeloma cells.
Isotype
IgG
Clonality
Monoclonal
Host
Mouse
Gene
SMC2
Purity
Protein A or G purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1-5 ug/ml
Theoretical MW
155 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at -20C. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.08% Sodium Azide
Purity
Protein A or G purified

Alternate Names for SMC2 Antibody (E1M)

  • CAP-E
  • CAPESMC2 structural maintenance of chromosomes 2-like 1 (yeast)
  • Chromosome-associated protein E
  • FLJ10093
  • hCAP-EXCAP-E homolog
  • SMC protein 2
  • SMC2 (structural maintenance of chromosomes 2, yeast)-like 1
  • SMC2 structural maintenance of chromosomes 2-like 1
  • SMC-2
  • SMC2L1
  • structural maintenance of chromosomes (SMC) family member
  • structural maintenance of chromosomes 2
  • structural maintenance of chromosomes protein 2

Background

CAP-E and CAP-C (Chromosome Associated Protein-E & C) are also SMC (Structural Maintenance of Chromosome) family members that form a heterodimeric complex required for mitotic chromosome condensation to achieve proper segregation of genetic information during subsequent cell division. hCAP-C/hCAP-E is a component of a multiprotein complex called condensin that interacts with phosphorylation of Histone H3 resulting in the mitotic chromosome condensation. The distribution patterns of the two heterodimeric complexes in interphase nucleus indicate independent behaviour of the two complexes during cell cycle. These results suggest that the two distinct complexes are involved in different aspects of mitotic chromosome organization in human cells.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol SMC2