RUNX2/CBFA1 Antibody [DyLight 405]


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Product Details

Reactivity Hu, MuSpecies Glossary
Applications ICC/IF, IHC, IHC-P
Please see the vial label for concentration. If unlisted please contact technical services.

RUNX2/CBFA1 Antibody [DyLight 405] Summary

A synthetic peptide made to an internal region of the human RUNX2 protein (within residues 300-375). [Swiss-Prot Q13950]
Immunogen affinity purified
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Packaging, Storage & Formulations

Store at 4C in the dark.
DyLight 405
DyLight 405 (A=400, E=420)
50mM Sodium Borate
0.05% Sodium Azide
Immunogen affinity purified


  • Immunocytochemistry/Immunofluorescence 1:100
  • Immunohistochemistry 1:200
  • Immunohistochemistry-Paraffin 1:200
Application Notes
This RUNX2 antibody is useful for ICC/IF and Immunohistochemistry-paraffin embedded sections. Prior to immunostaining paraffin tissues, antigen retrieval with sodium citrate buffer (pH 6.0) is recommended.

Reactivity Notes

Human and mouse.

Alternate Names for RUNX2/CBFA1 Antibody [DyLight 405]

  • Acute myeloid leukemia 3 protein
  • CBFA1
  • CBFA1MGC120022
  • Core-binding factor subunit alpha-1
  • MGC120023
  • PEA2-alpha A
  • PEBP2A
  • PEBP2aA1
  • PEBP2-alpha A
  • runt domain, alpha subunit 1
  • runt-related transcription factor 2
  • SL3/AKV core-binding factor alpha A subunit
  • SL3-3 enhancer factor 1 alpha A subunit


RUNX2 is a transcription factor that mediates the expression several downstream proteins, which affect osteoblast differentiation and mitotic progression. It also is important in monocyte activation, as it is upregulated in response to LPS infection. Through interaction with Twist 1 and Twist 2, RUNX2 regulates osteocalcin transcription, following parathyroid hormone signaling for bone loss repair. Ossification in skeletal formation is also partially regulated through RUNX2. Essentially, this transcription factor is responsible for many developmental and repair mechanisms in bone and collagen.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for RUNX2/CBFA1 Antibody (NBP1-77461V). (Showing 1 - 2 of 2 FAQ).

  1. We would like an anti-RUNX2 for IHC-P which share cross reactivity with Rat, but not with Human.
    • We don't have any data for our RUNX2 antibodies that confirms they will NOT detect the human protein. When we can confirm that an antibody will not react with a certain species, we display a (-) sign on the datasheet. Otherwise, if the species is not listed it means that it has not been tested.
  2. I would like to obtain the fluorescence spectra of RUNX2 antibody (dylight 405), the catolog number is NBP1-77461V.
    • The visual spectrum for Dylight 405 can be seen at the following link in the graph labeled 405nm Violet Laser. For more specific information regarding the fluorecent spectra for Dylight 405: The maximal Absorbance is 400nm, The maximal Emission is 420nm, The extinction coefficient is 30000 cm^-1M^-1, The stokes shift is 30.

Secondary Antibodies


Isotype Controls

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Contact Information

Product PDFs


Gene Symbol RUNX2

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