PAR1/Thrombin Receptor Antibody (N2-11)


Western Blot: PAR1/Thrombin Receptor Antibody (N2-11) [NBP1-71770] - Analysis of Thrombin Receptor expression in human testis using NBP1-71770.
Immunocytochemistry/ Immunofluorescence: PAR1/Thrombin Receptor Antibody (N2-11) [NBP1-71770] - Thrombin Receptor antibody was tested in HeLa cells with FITC (green). Nuclei and actin were counterstained with Dapi more
Immunohistochemistry: PAR1/Thrombin Receptor Antibody (N2-11) [NBP1-71770] - Analysis of Thrombin Receptor on mouse skin using NBP1-71770.
Western Blot: PAR1/Thrombin Receptor Antibody (N2-11) [NBP1-71770] - WB analysis of PAR1 in whole cell lysate of Neuro2A cell line using 4ug/ml concentration of PAR1 antibody (clone N2-11). The antibody detected a more

Product Details

Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
1 mg/ml

PAR1/Thrombin Receptor Antibody (N2-11) Summary

The oligopeptide CNATLDPRSFLL from human Thrombin Receptor. [Swiss-Prot# P25116]
Cell membrane; Multi-pass membrane protein.
Protein G purified
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Packaging, Storage & Formulations

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Tris-glycine, 150 mM NaCl
0.05% Sodium Azide
1 mg/ml
Protein G purified


  • Western Blot 1:250 - 1:1000
  • ELISA 1:100 - 1:2000
  • Immunocytochemistry/Immunofluorescence 1:50
  • Immunohistochemistry 1:100
  • Immunohistochemistry-Paraffin 1:100
Application Notes
This Thrombin Receptor (N2-11) antibody is useful for ELISA, Immunohistochemistry on paraffin-embedded sections, Immunocytochemistry/Immunofluorescence and Western blot, where a band can be seen at ~52 kDa. The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
52 kDa
Read Publications using
NBP1-71770 in the following applications:

Reactivity Notes

Human and mouse.

Alternate Names for PAR1/Thrombin Receptor Antibody (N2-11)

  • Cf2r
  • coagulation factor II (thrombin) receptor
  • Coagulation factor II receptor
  • F2R
  • HTR
  • PAR1
  • PAR1PAR-1protease-activated receptor 1
  • Protease-Activated Receptor 1
  • Thrombin receptor
  • ThrR
  • TRproteinase-activated receptor 1


Thrombin, the main effector protease of coagulation cascade, is a most potent platelet activator and its actions on platelets are mediated by Thrombin Receptors (also called platelet protease-activated receptors, PARs), which are GPCR members of 7-transmembrane domain receptor superfamily. PARs subtypes includes: PAR-1, PAR-2, PAR-3, and PAR-4, and in addition to platelets, they are also located in smooth muscle cells, endothelial cells, and fibroblasts. PAR1 or thrombin receptor (F2R) is a prototypical GPCR activated by thrombin's lowest concentration compared to other PARs and after cleavage of the extreme N-terminal peptide, the exposed tethered ligand of PAR1 activates itself for participation in diverse physiological processes including coagulation, inflammation, and vascular homeostasis. PAR1 knockout in mouse leads to death of pups in midgestation due to impaired vascular development as well as severe bleeding, whereas endothelial cell-specific reintroduction of PAR1 can rescue the phenotype. PAR1 has emerged as a target for anti-platelet therapies which are useful for ACS (acute coronary syndromes), stable coronary disease, ischemic atherothrombotic stroke, and peripheral arterial disease.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for PAR1/Thrombin Receptor Antibody (NBP1-71770)(2)

We have publications tested in 1 confirmed species: Mouse.

We have publications tested in 2 applications: ICC/IF, WB.

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Product General Protocols

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for PAR1/Thrombin Receptor Antibody (NBP1-71770). (Showing 1 - 1 of 1 FAQs).

  1. Would you be able to confirm whether or not the peptide immunogen used to generate NBP1-71770 - PAR1/Thrombin Receptor Antibody (N2-11) is available for purchase?
    • Unfortunately for NBP1-71770, this product is a licensed monoclonal and we do not have authority to provide the immunizing peptide for purchase.

Secondary Antibodies


Isotype Controls

Other Available Formats

Alexa Fluor (R) 405 Labeled NBP1-71770AF405
Alexa Fluor (R) 488 Labeled NBP1-71770AF488
Alexa Fluor (R) 647 Labeled NBP1-71770AF647
Alexa Fluor (R) 700 Labeled NBP1-71770AF700
Allophycocyanin Labeled NBP1-71770APC
Biotin Labeled NBP1-71770B
DyLight 350 Labeled NBP1-71770UV
DyLight 405 Labeled NBP1-71770V
DyLight 405LS Labeled NBP1-71770V3
DyLight 488 Labeled NBP1-71770G
DyLight 550 Labeled NBP1-71770R
DyLight 650 Labeled NBP1-71770C
DyLight 680 Labeled NBP1-71770FR
DyLight 755 Labeled NBP1-71770IR
FITC Labeled NBP1-71770F
HRP Labeled NBP1-71770H
PE Labeled NBP1-71770PE
PerCP Labeled NBP1-71770PCP

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Contact Information

Product PDFs


Gene Symbol F2R

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