PAR3/Thrombin Receptor-like 2 Antibody

Images

 
Immunohistochemistry-Paraffin: PAR3/Thrombin Receptor-like 2 Antibody [NLS261] - Pancreas, carcinoma
Immunohistochemistry-Paraffin: PAR3/Thrombin Receptor-like 2 Antibody [NLS261] - Analysis of anti-PAR3 antibody with human breast.
Immunohistochemistry-Paraffin: PAR3/Thrombin Receptor-like 2 Antibody [NLS261] - Breast, Carcinoma
Immunohistochemistry-Paraffin: PAR3/Thrombin Receptor-like 2 Antibody [NLS261] - Colon, Carcinoma

Order Details


    • Catalog Number
      NLS261
    • Availability
      Product Discontinued

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PAR3/Thrombin Receptor-like 2 Antibody Summary

Immunogen
Synthetic 14 amino acid peptide from C-terminus of human F2RL2.
Specificity
Human F2RL2. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Predicted Species
Monkey (93%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
F2RL2
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 5-10 ug/ml
  • Immunocytochemistry 1:10 - 1:500

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (86%).

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.1% Sodium Azide
Concentration
0.65 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PAR3/Thrombin Receptor-like 2 Antibody

  • Coagulation Factor II Receptor-like 2
  • F2RL2
  • PAR3
  • Protease-activated receptor 3
  • Thrombin Receptor-Like 2

Background

Proteinase-activated receptor 3 (PAR3) is a member of the Proteinase-Activated Receptor subfamily. The enzyme thrombin is involved in the activation of platelets, leukocytes, endothelial cells, and mesenchymal cells at sites of vascular injury. These cellular responses are triggered through proteolytic activation of PAR3 and other receptors by thrombin. It is believed that PAR3 functions as a cofactor for the cleavage and activation of PAR4. PAR3 expression has been documented in blood, bone marrow, lung, spleen, and vessel. ESTs have been isolated from head/neck, skeletal muscle, and skin libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Bioinformatics Tool for PAR3/Thrombin Receptor-like 2 Antibody (NLS261)

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Bioinformatics

Gene Symbol F2RL2
Entrez
Uniprot