PRODH Antibody - BSA Free

Immunohistochemistry-Paraffin: PRODH Antibody [NBP1-92288] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

• Reactivity: Hu
• Applications: IHC
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated
• Format: BSA Free

PRODH Antibody - BSA Free Summary

• Description: Novus Biologicals Rabbit PRODH Antibody - BSA Free (NBP1-92288) is a polyclonal antibody validated for use in IHC. Anti-PRODH Antibody: Cited in 1 publication. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: This antibody was developed against Recombinant Protein corresponding to amino acids: QESVAKLGIASRAEIEDWFTAETLGVSGTMDLLDWSSLIDSRTKLSKHLVVPNAQTGQLEPLLSRFTEEEELQMTRMLQRMDVLAKKATEMGVRLMVDAEQTYFQ
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PRODH
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:50 - 1:200
  • Immunohistochemistry-Paraffin 1:50 - 1:200
• Application Notes: For IHC-Paraffin, HIER pH 6 retrieval method is recommended.
• Control Peptide:

  PRODH Protein (NBP1-92288PEP)

Reactivity Notes

Immunogen displays the following percentage of sequence identity for non-tested species: Mouse (85%), Rat (83%)

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.2) and 40% Glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for PRODH Antibody - BSA Free

• EC 1.5.99.8
• FLJ33744
• HSPOX2
• mitochondrial
• p53-induced gene 6 protein
• PIG6MGC148078
• POX2
• PRODH2MGC148079
• proline dehydrogenase (oxidase) 1
• proline dehydrogenase (proline oxidase )
• Proline oxidase
• proline oxidase, mitochondrial
• SCZD4
• tumor protein p53 inducible protein 6

Background

The protein encoded by the PRODH gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PRODH Antibody (NBP1-92288)(1)

Publication using NBP1-92288

• Lee WJ, Cheng TC, Yen Y et al. Tea polyphenol epigallocatechin-3-gallate inhibits cell proliferation in a patient-derived triple-negative breast cancer xenograft mouse model via inhibition of proline-dehydrogenase-induced effects Journal of Food and Drug Analysis 2021-03-15 [PMID: 35696218]

Bioinformatics

• Gene Symbol: PRODH
• Entrez:
  • 5625(Human)
• Uniprot:
  • O43272(Human)