PRODH Products

Description

The protein encoded by the PRODH gene is a mitochondrial proline dehydrogenase that catalyzes the first step in proline degradation. Defects in this gene are a cause of hyperprolinemia type 1 and possibly susceptibility to schizophrenia 4 (SCZD4). The gene is located on chromosome 22q11.21, a region which has also been associated with the contiguous gene deletion syndromes DiGeorge syndrome and CATCH22 syndrome. (provided by RefSeq)

Bioinformatics

Entrez	5625 Human 19125 Mouse
Uniprot	O43272 Human NP_057419 Human
Product By Gene ID	5625
Alternate Names	Proline oxidase proline dehydrogenase (proline oxidase ) POX2 SCZD4 tumor protein p53 inducible protein 6 EC 1.5.99.8 proline oxidase, mitochondrial p53-induced gene 6 protein mitochondrial HSPOX2 PRODH2MGC148079 PIG6MGC148078 FLJ33744 proline dehydrogenase (oxidase) 1

Diseases related to PRODH

Discover more about diseases related to PRODH.

Schizophrenia
Digeorge Syndrome
Proline Dehydrogenase Deficiency
Psychotic Disorders
Malignant Neoplasms
Neoplasms
Mental Disorders
22q11 Deletion Syndrome
Bipolar Disorder
Schizoaffective Disorder
Haploinsufficiency
Physiological Stress
Hypoxia
Dehydration
Cell Transformation, Neoplastic
Dysequilibrium Syndrome
Autistic Disorder
Malnutrition
Epilepsy

Pathways for PRODH

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Cell Death
Transport
Prepulse Inhibition
Pathogenesis
Electron Transport
Hypersensitivity
Autophagy
Programmed Cell Death
Tricarboxylic Acid Cycle
Electron Transport Chain
Urea Cycle
Disease Resistance
Protein Palmitoylation
Cellular Homeostasis
Aging
Proteolysis
Neurogenesis
Nodulation
Fermentation
System Development

Research Areas for PRODH

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Apoptosis

PTMs for PRODH

Learn more about PTMs related to PRODH.

Oxidation
Methylation
Reduction
Phosphorylation
Nitration

Bioinformatics Tool for PRODH

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