POMT1 Antibody

Immunohistochemistry-Paraffin: POMT1 Antibody [NBP3-12487] - 1:100 dilution in IHC blocking buffer. DAB (brown) staining and Hematoxylin QS (blue) counterstain. 40x magnification.

• Reactivity: Hu, Mu, Rt
• Applications: WB, ELISA, IHC, IHC-P
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

POMT1 Antibody Summary

• Immunogen: Synthetic peptide taken within amino acid region 400-460 on human POMT1 protein.
• Clonality: Polyclonal
• Host: Rabbit
• Gene: POMT1
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA 1:10000
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:50-1:150
  • Western Blot 1:500

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: Contains Tris, HCl/glycine buffer (pH 7.4-7.8), 30% glycerol, 0.5% BSA, along with cryo-protective agents, and HEPES (exact storage and stabilization buffer information is proprietary).
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for POMT1 Antibody

• Dolichyl-phosphate-mannose--protein mannosyltransferase 1
• EC 2.4.1
• EC 2.4.1.109
• FLJ37239
• LGMD2K
• MDDGA1
• MDDGB1
• MDDGC1
• protein O-mannosyl-transferase 1
• protein-O-mannosyltransferase 1
• RT

Background

O-mannosylation is an important protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases. POMT1 shares sequence similarity with protein O-mannosyltransferases of S. cerevisiae. In yeast, these enzymes are located in the endoplasmic reticulum (ER) and are required for cell integrity and cell wall rigidity. POMT1 also shows similarity to the Drosophila 'rotated abdomen' (rt) gene, which when mutated causes defects in myogenesis and muscle structure.[supplied by OMIM]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: POMT1