Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC
Host: Rabbit Polyclonal
Species: Hu, Mu
Applications: WB, ELISA
Host: Rabbit Polyclonal
Species: Hu, Pm
Applications: WB
Host: Rabbit Polyclonal
Description
O-mannosylation is an important protein modification in eukaryotes that is initiated by an evolutionarily conserved family of protein O-mannosyltransferases. POMT1 shares sequence similarity with protein O-mannosyltransferases of S. cerevisiae. In yeast, these enzymes are located in the endoplasmic reticulum (ER) and are required for cell integrity and cell wall rigidity. POMT1 also shows similarity to the Drosophila 'rotated abdomen' (rt) gene, which when mutated causes defects in myogenesis and muscle structure.[supplied by OMIM]
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
10585 |
| Alternate Names |
- Dolichyl-phosphate-mannose--protein mannosyltransferase 1
- EC 2.4.1
- EC 2.4.1.109
- FLJ37239
- LGMD2K
- MDDGA1
- MDDGB1
- MDDGC1
- protein O-mannosyl-transferase 1
- protein-O-mannosyltransferase 1
- RT
|
