Pax6 Antibody (PAX6/498) [DyLight 680]

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Product Details

Summary
Reactivity Hu, Mu, Rt, ChSpecies Glossary
Applications WB, ELISA, Flow, ICC/IF, IHC-Fr
Clone
PAX6/498
Clonality
Monoclonal
Host
Mouse
Conjugate
DyLight 680

Order Details

Pax6 Antibody (PAX6/498) [DyLight 680] Summary

Immunogen
Recombinant fragment (N-terminus; aa 1-300) of human PAX6 protein
Localization
Nuclear
Marker
Stem Cell Marker
Specificity
Pax genes contain paired domains with strong homology to genes in Drosophila, which are involved in programming early development. Lesions in the Pax-6 gene account for most cases of aniridia, a congenital malformation of the eye, chiefly characterized by iris hypoplasia, which can cause blindness. Pax-6 is involved in other anterior segment malformations besides aniridia, such as Peters anomaly, a major error in the embryonic development of the eye with corneal clouding with variable iridolenticulocorneal adhesions. The Pax-6 gene encodes a transcriptional regulator that recognizes target genes through its paired-type DNA-binding domain. The paired domain is composed of two distinct DNA-binding subdomains, the amino-terminal subdomain and the carboxy-terminal subdomain, which bind respective consensus DNA sequences. The human Pax-6 gene produces two alternatively spliced isoforms that have the distinct structure of the paired domain.
Isotype
IgG1 Kappa
Clonality
Monoclonal
Host
Mouse
Gene
PAX6
Purity
Protein A purified
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Applications/Dilutions

Dilutions
  • Western Blot
  • ELISA
  • Flow Cytometry
  • Immunocytochemistry/Immunofluorescence
  • Immunohistochemistry-Frozen

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Protein A purified

Notes

Dylight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Pax6 Antibody (PAX6/498) [DyLight 680]

  • keratitis)
  • MGC17209
  • Oculorhombin
  • paired box 6
  • paired box protein Pax-6
  • Pax6

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol
ICC/IF Video Protocol

FAQs for Pax6 Antibody (NBP2-34705FR). (Showing 1 - 1 of 1 FAQ).

  1. What PAX6 antibody is recommend to use in ICC staining of human stem cells differentiated neural precursors?
    • By performing a search on PAX6 then refining this to antibodies which have been validated with human samples and for ICC, I can see that we have three products to meet your requirements. You can see all three of these antibodies. These products are listed based on sales and citations, however all of our antibodies are covered by our 100% guarantee to work in the species and applications listed on our website and on our product datasheets. You can read more about our quality guarantee here.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Alexa Fluor 350 NBP2-34705AF350
Alexa Fluor 405 NBP2-34705AF405
Alexa Fluor 488 NBP2-34705AF488
Alexa Fluor 532 NBP2-34705AF532
Alexa Fluor 594 NBP2-34705AF594
Alexa Fluor 647 NBP2-34705AF647
Alexa Fluor 700 NBP2-34705AF700
Alexa Fluor 750 NBP2-34705AF750
Allophycocyanin NBP2-34705APC
Allophycocyanin/Cy7 NBP2-34705APCCY7
Biotin NBP2-34705B
DyLight 350 NBP2-34705UV
DyLight 405 NBP2-34705V
DyLight 488 NBP2-34705G
DyLight 550 NBP2-34705R
DyLight 594 NBP2-34705DL594
DyLight 650 NBP2-34705C
DyLight 680 NBP2-34705FR
DyLight 755 NBP2-34705IR
HRP NBP2-34705H
Janelia Fluor 549 NBP2-34705JF549
Janelia Fluor 646 NBP2-34705JF646
PE NBP2-34705PE
PE/Atto594 NBP2-34705PEATT594
PE/Cy5.5 NBP2-34705PECY55
PE/Cy7 NBP2-34705PECY7
PerCP NBP2-34705PCP

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Bioinformatics Tool for Pax6 Antibody (NBP2-34705FR)

Discover related pathways, diseases and genes to Pax6 Antibody (NBP2-34705FR). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Blogs on Pax6.

Deriving neural precursor cells from human induced pluripotent stem cells
By Jennifer Sokolowski, MD, PhD.Human induced pluripotent stem cells (iPSCs) can be used to create models of human organ systems and are useful for a) ascertaining the mechanisms underlying pathological conditions...  Read full blog post.

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Bioinformatics

Gene Symbol PAX6