Glucagon Antibody (181402) [Unconjugated]

Images

 
Glucagon was detected in immersion fixed beta TC-6 mouse beta cell insulinoma cell line using 10 µg/mL Human/Mouse Glucagon Monoclonal Antibody (Catalog # MAB1249) for 3 hours at room temperature. Cells were ...read more
beta TC‑6 mouse beta cell insulinoma cell line was stained with Mouse Anti-Human/Mouse Glucagon Monoclonal Antibody (Catalog # MAB1249, filled histogram) or isotype control antibody (Catalog # MAB003, open ...read more

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications CyTOF-ready, Flow, ICC/IF
Clone
181402
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

Glucagon Antibody (181402) [Unconjugated] Summary

Immunogen
Human Glucagon synthetic peptide
Specificity
Detects human and mouse Glucagon.
Source
N/A
Isotype
IgG2a
Clonality
Monoclonal
Host
Mouse
Gene
GCG
Purity Statement
Protein A or G purified from hybridoma culture supernatant
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • CyTOF-ready
  • Immunocytochemistry 8-25 ug/mL
  • Intracellular Staining by Flow Cytometry 0.25 ug/10^6 cells
Reviewed Applications
Read 1 Review rated 3
using
MAB1249 in the following applications:

Publications
Read Publications using
MAB1249 in the following applications:

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Reconstitution Instructions
Reconstitute at 0.5 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Glucagon Antibody (181402) [Unconjugated]

  • GCG
  • glicentin-related polypeptide
  • GLP1
  • GLP-1
  • Glucagon
  • glucagon-like peptide 1
  • glucagon-like peptide 2
  • GRPP

Background

Glucagon is a 29 amino acid residue pancreatic peptide hormone. It stimulates gluconeogenesis and glycogenolysis to counter the glucose-lowering action of insulin.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for Glucagon Antibody (MAB1249)(8)

We have publications tested in 2 confirmed species: Human, Mouse.

We have publications tested in 5 applications: Flow Cytometry, ICC, IHC, IHC-P, Neutralization.


Filter By Application
Flow Cytometry
(2)
ICC
(1)
IHC
(3)
IHC-P
(1)
Neutralization
(1)
All Applications
Filter By Species
Human
(4)
Mouse
(4)
All Species
Showing Publications 1 - 8 of 8.
Publications using MAB1249 Applications Species
M Kohata, J Imai, T Izumi, J Yamamoto, Y Kawana, A Endo, H Sugawara, J Seiko, H Kubo, H Kawamura, T Sato, S Osaka, Y Munakata, Y Asai, S Kodama, K Takahashi, K Kaneko, H Katagiri Roles of FoxM1-driven basal beta-cell proliferation in maintenance of beta-cell mass and glucose tolerance during adulthood Journal of diabetes investigation, 2022-07-15;0(0):. 2022-07-15 [PMID: 35633298] (IHC, Mouse) IHC Mouse
Y Huang, E Motta, C Nanvuma, LD Kuhrt, Y Yuan, P Xia, M Lubas, S Zhu, M Schnauss, N Qazi, F Hu, H Zhang, T Lei, M Synowitz, C Flüh, H Kettenmann Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model Cell Reports, 2022-04-12;39(2):110670. 2022-04-12 [PMID: 35417708] (Neutralization, Mouse) Neutralization Mouse
XX Yu, WL Qiu, L Yang, YC Wang, MY He, D Wang, Y Zhang, LC Li, J Zhang, Y Wang, CR Xu Sequential progenitor states mark the generation of pancreatic endocrine lineages in mice and humans Cell Research, 2021-03-10;0(0):. 2021-03-10 [PMID: 33692492] (IHC, Mouse) IHC Mouse
P Rattanaamn, YM Roshorm, C Wilasrusme, N Proprom, B Ongphiphad, SC Talchai Direct suppression of human islet dedifferentiation, progenitor genes, but not epithelial to mesenchymal transition by liraglutide Heliyon, 2020-09-15;6(9):e04951. 2020-09-15 [PMID: 32995630] (Flow Cytometry, Human) Flow Cytometry Human
F Vecchio, N Lo Buono, A Stabilini, L Nigi, MJ Dufort, S Geyer, PM Rancoita, F Cugnata, A Mandelli, A Valle, P Leete, F Mancarella, PS Linsley, L Krogvold, KC Herold, HE Larsson, SJ Richardson, NG Morgan, K Dahl-Jørge, G Sebastiani, F Dotta, E Bosi, M Battaglia Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes JCI Insight, 2018-09-20;3(18):. 2018-09-20 [PMID: 30232284] (IHC-P, Human) IHC-P Human
Gomez D, O'Driscoll M, Sheets T, Hruban R, Oberholzer J, McGarrigle J, Shamblott M Neurogenin 3 Expressing Cells in the Human Exocrine Pancreas Have the Capacity for Endocrine Cell Fate. PLoS ONE, 2015-08-19;10(8):e0133862. 2015-08-19 [PMID: 26288179] (IHC, Human) IHC Human
Kornete , Mara, Beauchemin , Hugues, Polychronakos , Constant, Piccirillo , Ciriaco Pancreatic islet cell phenotype and endocrine function throughout diabetes development in non-obese diabetic mice. Autoimmunity, 2013-02-04;46(4):259-68. 2013-02-04 [PMID: 23256897] (Flow Cytometry, Mouse) Flow Cytometry Mouse
Ilancheran S, Michalska A, Peh G, Wallace EM, Pera M, Manuelpillai U Stem cells derived from human fetal membranes display multilineage differentiation potential. Biol. Reprod., 2007-05-09;77(3):577-88. 2007-05-09 [PMID: 17494917] (ICC, Human) ICC Human

Review for Glucagon Antibody (MAB1249) (1) 31

Average Rating: 3
(Based on 1 review)
We have 1 review tested in 1 species: Mouse.

Reviews using MAB1249:
Filter by Applications
IHC-P
(1)
All Applications
Filter by Species
Mouse
(1)
All Species
Images Ratings Applications Species Date Details
  3
reviewed by:
cynthia morimoto
IHC-P Mouse 02/04/2015
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Summary

ApplicationImmunohistochemistry-Paraffin
Sample TestedSee PMID 22069255
SpeciesMouse

FAQs for Glucagon Antibody (MAB1249) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

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Recent Reviews

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cynthia morimoto
02/04/2015
Application: IHC-P
Species: Mouse

Bioinformatics

Gene Symbol GCG