PAPOLA Antibody

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Immunoprecipitation: PAPOLA Antibody [NB100-55267] - Detection of Human PAPOLA on HeLa whole cell lysate using NB100-55267. PAPOLA was also immunoprecipitated by rabbit anti-PAPOLA antibody NB100-55268.

Product Details

Summary
Reactivity Hu, Mu, Rt, Po, Bv, Ca, Ch, Eq, GP, Pm, Rb, RM, TrSpecies Glossary
Applications IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1.0 mg/ml
 

Independent Antibodies

       

Order Details

PAPOLA Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 525 and 575 of human poly(A) polymerase alpha using the numbering given in entry NP_116021.2 (GeneID 10914).
Predicted Species
Mouse (100%), Rat (100%), Porcine (100%), Guinea Pig (100%), Bovine (100%), Rabbit (100%), Rhesus Macaque (100%), Chicken (100%), Canine (100%), Turkey (100%), Primate (100%), Equine (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
PAPOLA
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Immunoprecipitation 2 - 5 ug/mg lysate
Application Notes
Western Blot Not Recommended.

Reactivity Notes

Based on 100% sequence identity, this antibody is predicted to react with Panda, Orangutan, Gorilla, Chimpanzee, Sauropsida, Duckbill platypus, Tasmanian devil and Northern white-cheeked gibbon.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
Tris-Citrate/Phosphate (pH 7.0 - 8.0)
Preservative
0.09% Sodium Azide
Concentration
1.0 mg/ml
Purity
Immunogen affinity purified

Alternate Names for PAPOLA Antibody

  • EC 2.7.7
  • EC 2.7.7.19
  • PAP-alpha
  • PAPMGC5378
  • poly(A) polymerase alpha
  • Polynucleotide adenylyltransferase alpha

Background

PAPOLA is a polymerase that creates the 3' poly(A) tail of mRNA's. It is also required for the endoribonucleolytic cleavage reaction at some polyadenylation sites. PAPOLA may acquire specificity through interaction with a cleavage and polyadenylation specificity factor (CPSF) at its C-terminus.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Species: Hu, Mu, Rt, Po, Bv, Ca, Ch, Eq, GP, Pm, Rb, RM, Tr
Applications: IP

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol PAPOLA
Entrez
Uniprot