p66 beta Antibody

Images

 
Western Blot: p66 beta Antibody [NB100-60645] - Detection of Mouse p66beta/GATAD2B by Western Blot. Samples: Whole cell lysate (50 ug) from NIH3T3, TCMK-1, and CT26.WT cells. Antibodies: Affinity purified rabbit ...read more
Western Blot: p66 beta Antibody [NB100-60645] - Detection of Human p66beta/GATAD2B on HeLa whole cell lysate using NB100-60645. p66beta/GATAD2B was also immunoprecipitated by rabbit anti-p66beta/GATAD2B antibodies ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, IP
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
0.2 mg/ml
 

Independent Antibodies

 

Biological Strategies

     

Order Details

p66 beta Antibody Summary

Immunogen
The immunogen recognized by this antibody maps to a region between residue 1 and 50 of human transcription repressor p66 beta component of the MeCP1 complex (GATA zinc finger domain containing 2B ) using the numbering given in entry NP_065750.1 (GeneID 57
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
GATAD2B
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:2000-1:10000
  • Immunoprecipitation 2-5 ug/mg lysate
Theoretical MW
65 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Positive Control
p66 beta Lysate (NBL1-10987)
Publications
Read Publication using NB100-60645.

Packaging, Storage & Formulations

Storage
Store at 4C. Do not freeze.
Buffer
TBS and 0.1% BSA
Preservative
0.09% Sodium Azide
Concentration
0.2 mg/ml
Purity
Immunogen affinity purified

Alternate Names for p66 beta Antibody

  • FLJ37346
  • GATA zinc finger domain containing 2B
  • GATA zinc finger domain-containing protein 2B
  • KIAA1150
  • MGC138257
  • MGC138285
  • p66/p68
  • P66beta
  • RP11-216N14.6
  • transcription repressor p66 beta component of the MeCP1 complex
  • transcriptional repressor p66-beta

Background

P66beta/GATAD2B interacts with MBD2 (methyl-CpG-binding domain 2) and MBD3 (methyl-CpG-binding domain 3) and participates in transcriptional repression in association with the MBD2/NuRD and MBD3/NuRD histone deacetylase complexes. P66beta/GATAD2B is SUMOylated in vivo and its repressive activity has been shown to be enhanced by SUMOylation. Alternate names for P66beta/GATAD2B include transcriptional repressor p66 beta, p66/p68, GATA zinc-finger domain-containing protein 2B, FLJ37346, and KIAA1150.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Publications for p66 beta Antibody (NB100-60645)(1)

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Video Protocols

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Positive Control Lysate(s)

Secondary Antibodies

 

Isotype Controls

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Bioinformatics

Gene Symbol GATAD2B
Entrez
Uniprot