p63/TP73L Antibody (I27-I)

Immunohistochemistry-Paraffin: p63/TP73L Antibody (I27-I) [NBP3-08205] - Nuclear expression of p63/TP73L visualized with p63/TP73L antibody, clone I27-I, in basal cells of the prostatic glands. Formalin fixed, paraffin embedded human tissues (4 um sections) stained with p63/TP73L monospecific clonal antibody.

Immunohistochemistry-Paraffin: p63/TP73L Antibody (I27-I) [NBP3-08205] - Nuclear expression of p63 visualized with p63/TP73L antibody, clone I27-I, in normal hair follicles. Formalin fixed, paraffin embedded human tissues (4 um sections) stained with p63/TP73L monospecific clonal antibody.

Immunohistochemistry-Paraffin: p63/TP73L Antibody (I27-I) [NBP3-08205] - Nuclear expression of p63 visualized with p63/TP73L antibody, clone I27-I, in basal cell carcinoma of the skin. Formalin fixed, paraffin embedded human tissues (4 um sections) stained with p63/TP73L monospecific clonal antibody.

Immunohistochemistry-Paraffin: p63/TP73L Antibody (I27-I) [NBP3-08205] - Nuclear expression of p63/TP73L visualized with p63/TP73L antibody, clone I27-I, in squamous epithelium of the tonsil. Formalin fixed, paraffin embedded human tissues (4 um sections) stained with p63/TP73L monospecific clonal antibody.

• Reactivity: Hu
• Applications: IHC
• Clone: I27-I
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

p63/TP73L Antibody (I27-I) Summary

• Description: This antibody is immunoaffinity purified with immunogenic peptide as a ligand.
• Immunogen: Peptide derived from the internal sequence of human p63/TP73L. Antibody recognizes the epitope between Arg360 - His383.
• Localization: Nucleus
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: TP63
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:100-1:200
  • Immunohistochemistry-Paraffin 1:100-1:200

Packaging, Storage & Formulations

• Storage: Store at 4C.
• Buffer: 20 mM Tris-HCl, pH 8.0, 20 mg/ml BSA
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

This antibody is immunoaffinity purified with immunogenic peptide as a ligand.

Alternate Names for p63/TP73L Antibody (I27-I)

• amplified in squamous cell carcinoma
• Chronic ulcerative stomatitis protein
• CUSP
• EEC3
• EEC3B(p51B)
• Keratinocyte transcription factor KET
• KET
• KETRHS
• LMS
• OFC8
• OFC8SHFM4TP73LNBP
• p40
• p51
• p51tumor protein p53-like
• p53CP
• p63
• p63AIS
• p73H
• p73L
• p73LB(p51A)
• SHFM4
• TP53CP
• TP53L
• TP63
• TP73L
• Transformation-related protein 63
• tumor protein 63
• tumor protein p53-competing protein
• tumor protein p63 deltaN isoform delta
• tumor protein p63
• Tumor protein p73-like

Background

The p63 gene, a homologue of the tumor suppressor p53, is highly expressed in the basal or progenitor layers of many epithelial tissues. P63 shows remarkable structural similarity to p53 and to the related p73 gene. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TP63