Species: Hu
Applications: WB, IHC, ICC/IF
Host: Goat Polyclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
This gene encodes a member of the p53 family of transcription factors. An animal model, p63 -/- mice, has been useful in defining the role this protein plays in the development and maintenance of stratified epithelial tissues. p63 -/- mice have several developmental defects which include the lack of limbs and other tissues, such as teeth and mammary glands, which develop as a result of interactions between mesenchyme and epithelium. Mutations in this gene are associated with ectodermal dysplasia, and cleft lip/palate syndrome 3 (EEC3); split-hand/foot malformation 4 (SHFM4); ankyloblepharon-ectodermal defects-cleft lip/palate; ADULT syndrome (acro-dermato-ungual-lacrimal-tooth); limb-mammary syndrome; Rap-Hodgkin syndrome (RHS); and orofacial cleft 8. Both alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different proteins. Many transcripts encoding different proteins have been reported but the biological validity and the full-length nature of these variants have not been determined
Bioinformatics
| Entrez |
Human
Mouse
Rat
|
| Uniprot |
|
| Product By Gene ID |
8626 |
| Alternate Names |
- amplified in squamous cell carcinoma
- Chronic ulcerative stomatitis protein
- CUSP
- EEC3
- EEC3B(p51B)
- Keratinocyte transcription factor KET
- KET
- KETRHS
- LMS
- OFC8
- OFC8SHFM4TP73LNBP
- p40
- p51
- p51tumor protein p53-like
- p53CP
- p63
- p63AIS
- P73H
- p73L
- p73LB(p51A)
- SHFM4
- TP53CP
- TP53L
- TP63
- TP73L
- Transformation-related protein 63
- tumor protein 63
- tumor protein p53-competing protein
- tumor protein p63 deltaN isoform delta
- tumor protein p63
- Tumor protein p73-like
|
![Immunohistochemistry p63/TP73L Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/p63_AF1916_Immunohistochemistry_16919.jpg)
![Immunocytochemistry p63/TP73L Antibody [Unconjugated]](http://images.novusbio.com/fullsize2/p63_AF1916_Immunocytochemistry__Immunofluorescence_16973.jpg)
![Immunocytochemistry/ Immunofluorescence p63/TP73L Antibody [Unconjugated]](http://images.novusbio.com/fullsize/af1916_human-p63-tp73l-affinity-purified-polyclonal-ab-41202412401237.jpg)
![Immunocytochemistry/ Immunofluorescence p63/TP73L Antibody [Unconjugated]](http://images.novusbio.com/fullsize/antibody/af1916_human-p63-tp73l-affinity-purified-polyclonal-ab-2362025103050.jpg)
