OSCAR Antibody [Biotin]

• Reactivity: Mu
• Applications: WB
• Clonality: Polyclonal
• Host: Goat
• Conjugate: Biotin
• Concentration: LYOPH

OSCAR Antibody [Biotin] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse OSCAR
  Asp19-Asn228
  Accession # Q8VBT3
• Specificity: Detects mouse OSCAR in Western blots.
• Source: N/A
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: OSCAR
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 0.1 ug/mL
• Readout System:
  • Streptavidin Native Protein NBP2-29367
  • Streptavidin Native Protein NBP2-29370
  • Streptavidin Native Protein NBP2-29371

Packaging, Storage & Formulations

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
• Buffer: Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
• Preservative: No Preservative
• Concentration: LYOPH
• Reconstitution Instructions: Reconstitute at 0.2 mg/mL in sterile PBS.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for OSCAR Antibody [Biotin]

• hOSCAR
• MGC33613
• OSCAR
• osteoclast associated receptor OSCAR-S1
• osteoclast associated receptor OSCAR-S2
• osteoclast associated, immunoglobulin-like receptor
• osteoclast-associated immunoglobulin-like receptor
• Osteoclast-associated receptor
• PIgR3
• PIgR-3
• Poly-Ig receptor 3
• Polymeric immunoglobulin receptor 3

Background

OSCAR is a type I transmembrane protein that may be a bone-specific regulator of osteoclast differentiation. It contains two extracellular Ig-like domains that share homology with mouse PIR (Paired immunoglobulin-like receptor) family proteins and members of the human Leukocyte Receptor Complex (LRC)-encoded proteins.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for OSCAR Antibody (BAF1633)(1)

Publication using BAF1633

• Negishi-Koga T, Gober H, Sumiya E, Komatsu N, Okamoto K, Sawa S, Suematsu A, Suda T, Sato K, Takai T, Takayanagi H Immune complexes regulate bone metabolism through FcRgamma signalling. Nat Commun, 2015-03-31;6(0):6637. 2015-03-31 [PMID: 25824719] (Flow Cytometry, Mouse)

Bioinformatics

• Gene Symbol: OSCAR
• Uniprot:
  • Q8VBT3()