OSCAR Products

Description

Osteoclasts are multinucleated cells that resorb bone and are essential for bone homeostasis. This gene encodes an osteoclast-associated receptor (OSCAR), which is a member of the leukocyte receptor complex (LRC) protein family that plays critical roles in the regulation of both innate and adaptive immune responses. Different from the other LRC members, OSCAR expression is detected specifically in preosteoclasts or mature osteoclasts. OSCAR may be an important bone-specific regulator of osteoclast differentiation. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq]

Bioinformatics

Uniprot	NM_133169 Human NM_206818 Human NP_570127 Human NP_996554.1 Human Q8IYS5 Human Q8VBT3 Mouse
Product By Gene ID	126014
Alternate Names	hOSCAR MGC33613 osteoclast associated receptor OSCAR-S1 osteoclast associated receptor OSCAR-S2 osteoclast associated, immunoglobulin-like receptor osteoclast-associated immunoglobulin-like receptor Osteoclast-associated receptor PIgR3 PIGR3 PIgR-3 Poly-Ig receptor 3 Polymeric immunoglobulin receptor 3